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Dominique Guianvarc'h

Professeure

Université Paris-Saclay Faculté des Sciences d'Orsay

France

Research Interests

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Professors in France Professors in Organic Chemistry Organic Chemistry professors in France

About

Dominique Guianvarc'h is a Professor at Université Paris-Sud Faculté des Sciences d'Orsay in France. Her research focuses on chemical biology, particularly in the synthesis and application of bioorthogonal probes and mycolic acids. Recent publications highlight her work on methods for real-time monitoring of hydrogen peroxide in live cells, as well as the study of unique post-translational modifications in bacteria. She is actively engaged in advancing the field of chemistry within life sciences through innovative research and collaborative symposia.

Articles (21)

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Collaborators (17)

Paola B. Arimondo

Institut Pasteur

FRANCE

Dominique Guianvarc'h

Research Interests

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Articles (21)

Sydnone-modified nucleosides as versatile tools for bioorthogonal post-synthetic functionalization of antisense oligonucleotides

Synthesis and Evaluation of the First Generation of Glycosylated Nucleoside Analogues as Potential Inhibitors of the Base J Metabolism in Kinetoplastid Parasites

Oligonucleotides Post‐Synthetic Modifications: An Overview of Clickable Nucleoside Phosphoramidites Suitable for Solid‐Phase Synthesis

Synthesis of Bioorthogonal Mycolic Acids: Chemoselective Reduction of β‐Ketoesters Containing an Alkyne Using the Noyori Catalyst

Synthetic mycolates derivatives to decipher protein mycoloylation, a unique post-translational modification in bacteria

Borinic Acid-Based Fluorogenic Probes as an Alternative to the Amplex Red Assay for Real-Time H<sub>2</sub>O<sub>2</sub> Monitoring in Live Cells

PSL Chemical Biology Symposia: The Increasing Impact of Chemistry in Life Sciences

Oligonucleotide‐Based Photoaffinity Probes: Chemical Tools and Applications for Protein Labeling

Bioorthogonal Monomycolate of Trehalose Disclosed the <i>O</i>-Mycoloylation of Mycoloyltransferases and Other Cell Envelope Proteins in <i>C. glutamicum</i>

Foreword—Breaking barriers in chemical biology: the innovative tour de force of the ChemBio GDR

PSL Chemical Biology Symposia Third Edition: A Branch of Science in its Explosive Phase

Preparation of 5‐Hydroxymethyl‐pyrimidine Based Nucleosides: A Reinvestigation

Fast Access to 5-Hydroxymethyl Derivatives of 2′-Deoxyuridine Promoted by Acidic Amberlyst 15 Resin

2′-Modified Thymidines with Bioorthogonal Cyclopropene or Sydnone as Building Blocks for Copper-Free Postsynthetic Functionalization of Chemically Synthesized Oligonucleotides

Synthesis of trehalose-based chemical tools for the study of the mycobacterial membrane

Synthesis of chemical tools to label the mycomembrane of corynebacteria using modified iron(iii) chloride-mediated protection of trehalose

Hydrogen Peroxide‐Responsive Triggers Based on Borinic Acids: Molecular Insights into the Control of Oxidative Rearrangement

Hydrogen peroxide–responsive triggers based on borinic acids: molecular insights into the control of oxidative rearrangement

Characterization of SET-Domain Histone Lysine Methyltransferase Substrates Using a Cofactor S-Adenosyl-l-Methionine Surrogate

Synthesis of chemical tools to label the mycomembrane of corynebacteria using a modified Iron (III) chloride-mediated protection of trehalose

Evaluation of borinic acids as new, fast hydrogen peroxide-responsive triggers

Collaborators (17)

Paola B. Arimondo

Frédéric Taran

Nicolas Bayan

Dominique Urban

Raphaël Rodriguez

Philippe Karoyan

Philippe Grellier

Boris Vauzeilles

Eric Defrancq

Emilie Lesur

Clotilde Policar

Yann Bourdreux

Christine Gaillet

Marie Lopez

Tatiana Cañeque

Christophe Biot

Gilles Doisneau

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