Emma Bolderson

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Senior Research Fellow / Senior Lecturer

Queensland University of Technology

Australia

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hSSB1: A key regulator of genome stability and potential cancer therapeutic target

Open Date: 2014-01-01

Close Date: 2016-01-01

Articles (16)

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Collaborators (8)

Mark Adams

Queensland University of Technology

AUSTRALIA

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Luke Guddat

Professor

University of Queensland

AUSTRALIA

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Neha S. Gandhi

Queensland University of Technology

AUSTRALIA

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Pascal Duijf

Associate Professor

University of South Australia

AUSTRALIA

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Kienan Savage

Reader/Group Leader

The Queen's University Belfast

UNITED KINGDOM

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Kenneth O'Byrne

Queensland University of Technology

AUSTRALIA

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Derek Richard

Queensland University of Technology

AUSTRALIA

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Amila Suraweera

Research Fellow/Lecturer

Queensland University of Technology

AUSTRALIA

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Emma Bolderson

Research Interests

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Recent Grants

Articles (16)

Targeting the hSSB1-INTS3 Interface: A Computational Screening Driven Approach to Identify Potential Modulators

Sequence- and Structure-Dependent Cytotoxicity of Phosphorothioate and 2'-O-Methyl Modified Single-Stranded Oligonucleotides.

Inhibition of Aurora B kinase (AURKB) enhances the effectiveness of 5-fluorouracil chemotherapy against colorectal cancer cells.

Structural investigation of CDCA3‐Cdh1 protein–protein interactions using in vitro studies and molecular dynamics simulation

hSSB1 (NABP2/OBFC2B) modulates the DNA damage and androgen-induced transcriptional response in prostate cancer

The fructose-bisphosphate, Aldolase A (ALDOA), facilitates DNA-PKcs and ATM kinase activity to regulate DNA double-strand break repair

Mono-phosphorylation at Ser4 of barrier-to-autointegration factor (Banf1) significantly reduces its DNA binding capability by inducing critical changes in its local conformation and DNA binding surface

Targeting the COMMD4–H2B protein complex in lung cancer

Beyond PARP1: The Potential of Other Members of the Poly (ADP-Ribose) Polymerase Family in DNA Repair and Cancer Therapeutics

The role of inner nuclear membrane proteins in tumourigenesis and as potential targets for cancer therapy

Cell Metabolism and DNA Repair Pathways: Implications for Cancer Therapy

Barrier-To-Autointegration-factor (Banf1) modulates DNA double-strand break repair pathway choice via regulation of DNA-dependent kinase (DNA-PK) activity

COMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double-strand breaks

Elevating CDCA3 Levels Enhances Tyrosine Kinase Inhibitor Sensitivity in TKI-Resistant EGFR Mutant Non-Small-Cell Lung Cancer

Elevating CDCA3 levels in non-small cell lung cancer enhances sensitivity to platinum-based chemotherapy

Identification of Proteins Deregulated by Platinum-Based Chemotherapy as Novel Biomarkers and Therapeutic Targets in Non-Small Cell Lung Cancer.

Collaborators (8)

Mark Adams

Luke Guddat

Neha S. Gandhi

Pascal Duijf

Kienan Savage

Kenneth O'Byrne

Derek Richard

Amila Suraweera

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