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Francesco Fiorentino

Assistant Professor of Biochemistry

Sapienza University of Rome

Italy

Research Interests

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Professors in Italy Professors in Biochemistry Biochemistry professors in Italy

Articles (20)

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2026

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2025

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2025

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2025

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2025

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2025

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2025

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2025

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2025

Collaborators (16)

Clemens Zwergel

Tenure-track Assistant Professor RTT

Sapienza University of Rome

ITALY

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Gianluca Sbardella

DIRETTORE DI DIPARTIMENTO

Università degli Studi di Napoli Federico II

ITALY

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Xiaodong Cheng

The University of Texas MD Anderson Cancer Center

UNITED STATES

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Cheryl H. Arrowsmith

Chief Scientist

University of Toronto

CANADA

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Melanie McDowell

Max Planck Research Group Leader

Max Planck Institute of Biophysics

GERMANY

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Anand D. Jeyasekharan

National University of Singapore (NUS)

SINGAPORE

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EUGENIA BELCASTRO

University of Pisa

ITALY

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Antonello Mai

Sapienza University of Rome

ITALY

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Cecilia Bombelli

Sapienza University of Rome

ITALY

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Tobias Madl

Head of Otto Loewi Research Center; Full Professor and Head of Division Medicinal Chemistry

Medical University of Graz

AUSTRIA

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Leonhard H. Urner

Independent Group Leader and lecturer

Technische Universität Dortmund

GERMANY

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Dante Rotili

Full Professor of Medicinal Chemistry

Roma Tre University

ITALY

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Stefania Petrini

Biologo Ricercatore e Responsabile strutturato della Facility di Microscopia

Ospedale Pediatrico Bambino Gesù

ITALY

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Ernesto Guccione

Professor

Icahn School of Medicine at Mount Sinai

UNITED STATES

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Sara Marchese

Università degli Studi di Pavia

ITALY

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Alessia CIOGLI

Associate Professor

Sapienza University of Rome

ITALY

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Francesco Fiorentino

Research Interests

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Articles (20)

A synergistic interaction between PRMT5 and LSD1 inhibitors in AML

Simplification and Derivatization of Quinoline-Containing M41 Lead to the Discovery of NADPH Oxidase Isoform-Selective Inhibitors Effective in Cancer Cells

Native Mass Spectrometry of Soluble Proteins with Sodium Chloride Enabled by a Dendritic Detergent

METTL3–METTL14 Heterodimer Assembly Enables Multivalent RNA Engagement and Is Tuned by Interface-Targeting Peptides

METTL1/WDR4 Complex: A Novel Epitranscriptomic Target at the Crossroads of RNA Methylation and Drug Discovery

Development of High-Affinity CHD1 Chromodomain Inhibitors

Development of Biphenyl-Substituted Uracil-Based Hydroxamic Acids (UBHAs) as Potent HDAC Inhibitors with Pro-Apoptotic Activity in Leukemia and Prostate Cancer Cells

The ATC12 small molecule inhibits the Aurora-A/TPX2 interaction and impairs the proliferation of breast cancer cells

Sirtuin modulators: a review of patents from 2020 to 2024

Deubiquitinase-targeting chimeras (DUBTACs). A game-changing approach for targeted protein stabilization in drug discovery

Exploring the role of conformational restriction in 5-alkyl-6-benzyl-2-{[(methylthio)methyl]thio}pyrimidin-4(3H)-ones. Effects in HIV-1 infected cells and reverse transcriptase enzymes

Systematic structure–activity relationship investigation on novel 5-alkyl-6-benzyl-2-{[(methylthio/phenylthio)alkyl]thio}-pyrimidin-4(3H)-ones endowed with potent anti-hiv-1 activity

Optimization of Lipoplexes Functionalized with a Sialic Acid Mimetic (F9-PEG) to Target the C1858T PTPN22 Variant for Preclinical Assessment of a Novel Immunotherapy in Endocrine Autoimmunity

Development of C646‐Based Proteolysis Targeting Chimeras Degraders of the Lysine Acetyltransferases CBP and p300

Native mass spectrometry for proximity-inducing compounds: a new opportunity for studying chemical-induced protein modulation

An Amazing 30-Year Journey around the DABO Family: A Medicinal Chemistry Lesson on a Versatile Class of Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors

Quinoline-Based DNA Methyltransferase Inhibitors Featuring Basic Side Chains: Design, Synthesis, and Insight in Biochemical and Anticancer Cell Properties

Correction: Sennato et al. Optimization of Lipoplexes Functionalized with a Sialic Acid Mimetic (F9-PEG) to Target the C1858T PTPN22 Variant for Preclinical Assessment of a Novel Immunotherapy in Endocrine Autoimmunity. Pharmaceutics 2025, 17, 710

Structural characterisation of the fungal Pmt4 homodimer

Structural snapshots of Pseudomonas aeruginosa LptB2FG and LptB2FGC reveal insights into lipopolysaccharide recognition and transport

Collaborators (16)

Clemens Zwergel

Gianluca Sbardella

Xiaodong Cheng

Cheryl H. Arrowsmith

Melanie McDowell

Anand D. Jeyasekharan

EUGENIA BELCASTRO

Antonello Mai

Cecilia Bombelli

Tobias Madl

Leonhard H. Urner

Dante Rotili

Stefania Petrini

Ernesto Guccione

Sara Marchese

Alessia CIOGLI

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