Gerry Nicolaes

University of Maastricht

Netherlands

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Articles (19)

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2025

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2022

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2021

Collaborators (16)

Johan Heemskerk

Emeritus Prof. of Cell Biochemistry of Thrombosis and Haemostasis

University of Maastricht

NETHERLANDS

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Kerstin Jurk

University Medical Center of the Johannes Gutenberg University Mainz

GERMANY

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Bartolo Ferraro

Ludwig Maximilian University

GERMANY

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Mauro Perretti

Professor at Queen Mary University of London

Queen Mary University of London

UNITED KINGDOM

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Joram Huckriede

University of Maastricht

NETHERLANDS

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Erik Biessen

University of Maastricht

NETHERLANDS

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Marcel van de Poll

NETHERLANDS

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Stephanie Franzén

Associate Professor

Uppsala University

SWEDEN

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Stijn Agten

University of Maastricht

NETHERLANDS

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Pablo García de Frutos

Head of Department

SPAIN

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Kanin Wichapong

University of Maastricht

NETHERLANDS

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Tilman Hackeng

University of Maastricht

NETHERLANDS

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Rolf Boelens

Utrecht University

NETHERLANDS

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chris reutelingsperger

Professor

NETHERLANDS

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Anders Bergqvist

Uppsala University

SWEDEN

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Miklós Lipcsey

Uppsala University

SWEDEN

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Gerry Nicolaes

Research Interests

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Articles (19)

Proteolytic neutralization of extracellular histones by neutrophil elastase is enhanced by heparin

A phase I trial evaluating the safety, tolerability, pharmacokinetics and pharmacodynamics of intravenously administered low-anticoagulant heparin (M6229) in critically ill sepsis patients

Trp1250, Lys1252 and Arg1367 of ADAMTS13 comprise a hot-spot for anti-CUB domain antibodies in patients with iTTP

CCL18 aggravates atherosclerosis by inducing CCR6-dependent T-cell influx and polarization

The IRAK-M death domain

M6229 Protects against Extracellular-Histone-Induced Liver Injury, Kidney Dysfunction, and Mortality in a Rat Model of Acute Hyperinflammation

Association of corticosteroid therapy with reduced acute kidney injury and lower NET markers in severe COVID-19

Elevated levels of citrullinated fibrinogen in patients with cancer

The role of extracellular histones in COVID‐19

Extracellular histone release by renal cells after warm and cold ischemic kidney injury: Studies in an ex-vivo porcine kidney perfusion model

Inhibition of Neutral Sphingomyelinase 2 by Novel Small Molecule Inhibitors Results in Decreased Release of Extracellular Vesicles by Vascular Smooth Muscle Cells and Attenuated Calcification

Design and characterization of novel activated protein C variants for the proteolysis of cytotoxic extracellular histone H3

Multimodal measurement of glycocalyx degradation during coronary artery bypass grafting

Impaired Antibody Response Is Associated with Histone-Release, Organ Dysfunction and Mortality in Critically Ill COVID-19 Patients

Structural anomalies in a published NMR-derived structure of IRAK-M

Structure-Based Cyclic Glycoprotein Ibα-Derived Peptides Interfering with von Willebrand Factor-Binding, Affecting Platelet Aggregation under Shear

Design, synthesis, and biological evaluation of novel pyrrolidinone small-molecule Formyl peptide receptor 2 agonists

Histone H3 Cleavage in Severe COVID-19 ICU Patients

Evolution of NETosis markers and DAMPs have prognostic value in critically ill COVID-19 patients

Collaborators (16)

Johan Heemskerk

Kerstin Jurk

Bartolo Ferraro

Mauro Perretti

Joram Huckriede

Erik Biessen

Marcel van de Poll

Stephanie Franzén

Stijn Agten

Pablo García de Frutos

Kanin Wichapong

Tilman Hackeng

Rolf Boelens

chris reutelingsperger

Anders Bergqvist

Miklós Lipcsey

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