Martine Smit

University of Amsterdam

Netherlands

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Articles (14)

Year:

2024

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2024

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2024

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2024

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2021

Collaborators (20)

Carl White

University of Western Australia

AUSTRALIA

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Claudia V. Perez Almeria

University of Amsterdam

NETHERLANDS

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Raimond Heukers

Chief Scientific Officer

QVQ Holding BV

NETHERLANDS

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Jelle van den Bor

University of Amsterdam

NETHERLANDS

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Christian Ottmann

NETHERLANDS

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I.J.P. de Esch

University of Amsterdam

NETHERLANDS

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Nick Bergkamp

University of Amsterdam

NETHERLANDS

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Nicholas Casewell

Professor of Tropical Disease Biology

Liverpool School of Tropical Medicine

UNITED KINGDOM

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Brian F. Volkman

Medical College of Wisconsin

UNITED STATES

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Caitrin Crudden

University of Amsterdam

NETHERLANDS

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Chris de Graaf

Senior Director, Head of Computational Chemistry

UNITED KINGDOM

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Julien Slagboom

University of Amsterdam

NETHERLANDS

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Maarten Bebelman

University of Amsterdam

NETHERLANDS

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Aitor Casas-Sanchez

Lecturer

Liverpool School of Tropical Medicine

UNITED KINGDOM

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Robert Jefferson

Lecturer (Assistant Professor)

King’s College London

UNITED KINGDOM

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Jeffrey Roy van Senten

Københavns Universitet

DENMARK

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Icaro Ariel Simon

University of Amsterdam

NETHERLANDS

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Laura E. Kilpatrick

UNITED KINGDOM

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Gunnar W. Klau

Professor

Heinrich Heine University Düsseldorf

GERMANY

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Giancarlo Biagini

Deputy Head of Department (Professor)

Liverpool School of Tropical Medicine

UNITED KINGDOM

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Martine Smit

Research Interests

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Articles (14)

Pharmacological Characterization and Radiolabeling of VUF15485, a High-Affinity Small-Molecule Agonist for the Atypical Chemokine Receptor ACKR3

Multivalent CXCR4-targeting nanobody formats differently affect affinity, receptor clustering, and antagonism

Structural basis for selectivity and antagonism in extracellular GPCR-nanobodies

G protein-coupled receptors

A virally encoded GPCR drives glioblastoma through feed-forward activation of the SK1-S1P 1 signaling axis

Exosomal release of the virus-encoded chemokine receptor US28 contributes to chemokine scavenging

Monitoring Snake Venom-Induced Extracellular Matrix Degradation and Identifying Proteolytically Active Venom Toxins Using Fluorescently Labeled Substrates

NanoB2 to monitor interactions of ligands with membrane proteins by combining nanobodies and NanoBRET

Computationally designed GPCR quaternary structures bias signaling pathway activation

Fragment Screening Yields a Small-Molecule Stabilizer of 14-3-3 Dimers That Modulates Client Protein Interactions

Fluorescently tagged nanobodies and NanoBRET to study ligand-binding and agonist-induced conformational changes of full-length EGFR expressed in living cells

Fusicoccin-A Targets Cancerous Inhibitor of Protein Phosphatase 2A by Stabilizing a C-Terminal Interaction with 14-3-3

Conformational selection guides β-arrestin recruitment at a biased G protein–coupled receptor

SARS-CoV-2 infects an upper airway model derived from induced pluripotent stem cells

Collaborators (20)

Carl White

Claudia V. Perez Almeria

Raimond Heukers

Jelle van den Bor

Christian Ottmann

I.J.P. de Esch

Nick Bergkamp

Nicholas Casewell

Brian F. Volkman

Caitrin Crudden

Chris de Graaf

Julien Slagboom

Maarten Bebelman

Aitor Casas-Sanchez

Robert Jefferson

Jeffrey Roy van Senten

Icaro Ariel Simon

Laura E. Kilpatrick

Gunnar W. Klau

Giancarlo Biagini

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