Hirokazu Hirai

Professor & Chair

Gunma University Graduate School of Medicine

Japan

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Hirokazu Hirai is a Professor & Chair at Gunma University Graduate School of Medicine, Japan. His research focuses on neurobiology, particularly in relation to Spinocerebellar Ataxia, chaperone-mediated autophagy, and the roles of various proteins in neuronal function. Recent publications include studies on animal models for neurological diseases and the effects of specific compounds on cerebellar Purkinje cells.

Articles (11)

Year:

2024

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2022

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2022

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2022

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2022

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2022

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2022

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2022

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2022

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2022

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2021

Collaborators (13)

Shigeki Takeda

JAPAN

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Hideki Uosaki

Associate Professor

Jichi Medical University

JAPAN

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Jan Cendelín

Charles University, Faculty of Medicine in Pilsen

CZECH REPUBLIC

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Masashi Watanave

Gunma University

JAPAN

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Hiroshi Katsuki

Professor

Kumamoto University

JAPAN

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Nobutake Hosoi

Lecturer

Gunma University Graduate School of Medicine

JAPAN

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Shigeru Yanagi

Gakushuin University

JAPAN

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Kaoru Inokuchi

Distinguished Professor

University of Toyama

JAPAN

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Noriaki Ohkawa

Dokkyo Medical University

JAPAN

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Takeshi Yasui

Assistant Professor

Nagoya University

JAPAN

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Ayumu Sugiura

Juntendo University

JAPAN

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Takahiro Seki

Visiting Professor

Kumamoto University

JAPAN

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Ayumu Konno

Lecturer

Gunma University

JAPAN

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Hirokazu Hirai

Research Interests

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Articles (11)

Production of Spinocerebellar Ataxia Type 3 Model Mice by Intravenous Injection of AAV-PHP.B Vectors

Protein kinase Cγ in cerebellar Purkinje cells regulates Ca 2+ -activated large-conductance K + channels and motor coordination

Development of novel potent ligands for GPR85, an orphan G protein-coupled receptor expressed in the brain

A cortical cell ensemble in the posterior parietal cortex controls past experience-dependent memory updating

D-Cysteine Activates Chaperone-Mediated Autophagy in Cerebellar Purkinje Cells via the Generation of Hydrogen Sulfide and Nrf2 Activation

Consensus Paper: Strengths and Weaknesses of Animal Models of Spinocerebellar Ataxias and Their Clinical Implications

Electrophysiological and Imaging Analysis of GFP-Tagged Protein Kinase C γ Translocation in Cerebellar Purkinje Cells

Plasticity of neural connections underlying oxytocin-mediated parental behaviors of male mice

Protective roles of MITOL against myocardial senescence and ischemic injury partly via Drp1 regulation

The neurotoxic effect of lactational PFOS exposure on cerebellar functional development in male mice

Ataxic phenotype and neurodegeneration are triggered by the impairment of chaperone-mediated autophagy in cerebellar neurons

Collaborators (13)

Shigeki Takeda

Hideki Uosaki

Jan Cendelín

Masashi Watanave

Hiroshi Katsuki

Nobutake Hosoi

Shigeru Yanagi

Kaoru Inokuchi

Noriaki Ohkawa

Takeshi Yasui

Ayumu Sugiura

Takahiro Seki

Ayumu Konno

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