Hitoshi Takizawa

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Vice Director and Professor

Kumamoto University

Japan

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About

Hitoshi Takizawa is the Vice Director and Professor at Kumamoto University in Japan. His research primarily focuses on hematopoietic stem cells, the role of mitochondrial translation in erythroid differentiation, and the implications of the microbiome in aging and immune response. Recent publications include studies on the effects of pharmacological agents on hematopoietic cells and the interaction between microbial signals and tissue repair processes.

Recent Grants

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Proteostasis crisis in erythropoiesis mediated by abnormal tRNA modification

Open Date: 2022-04-01

Close Date: 2024-03-01

Grant: Close

Formation of perinatal hematopoiesis in bone marrow

Open Date: 2021-04-01

Close Date: 2024-03-01

Grant: Close

Modulation of immune memory in blood stem cell toward effective host defense

Open Date: 2021-01-01

Close Date: 2023-01-01

Grant: Close

Reviving Immune Surveillance by Inscribing Immune Competent Code

Open Date: 2019-11-01

Close Date: 2020-03-01

Grant: Close

Cross-organ hematopoietic stem cell dynamics during development

Open Date: 2018-04-01

Close Date: 2021-03-01

Articles (17)

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2022

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2022

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2022

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2021

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2021

Collaborators (26)

Toshio Suda

JAPAN

Hitoshi Takizawa

Research Interests

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About

Recent Grants

Articles (17)

Mitochondrial translation regulates terminal erythroid differentiation by maintaining iron homeostasis

Microbiome and Hemato-immune Aging

Expansion effect of romiplostim on hematopoietic stem and progenitor cells versus thrombopoietin and eltrombopag.

Mobilization dynamics of bone marrow hematopoietic stem cells during hematopoietic regeneration

Integrin-α9 overexpression underlies the niche-independent maintenance of leukemia stem cells in acute myeloid leukemia

Activation of NOTCH signaling impedes cell proliferation and survival in acute megakaryoblastic leukemia

Akkermansia muciniphila induces slow extramedullary hematopoiesis via cooperative IL‐1R/TLR signals

IMPDH inhibition activates TLR‐VCAM1 pathway and suppresses the development of MLL‐fusion leukemia

Hematopoietic stem and progenitor cells integrate microbial signals to promote post‐inflammation gut tissue repair

Bone marrow imaging reveals the migration dynamics of neonatal hematopoietic stem cells

Quantitative Analysis of Sympathetic and Nociceptive Innervation Across Bone Marrow Regions in Mice

Unique molecular and functional features of extramedullary hematopoietic stem and progenitor cell reservoirs in humans

Author Correction: Remote control of neural function by X-ray-induced scintillation

IL-1 mediates microbiome-induced inflammaging of hematopoietic stem cells in mice

Inflammation Regulates Haematopoietic Stem Cells and Their Niche

Remote control of neural function by X-ray-induced scintillation

CD271+CD51+PALLADIN− Human Mesenchymal Stromal Cells Possess Enhanced Ossicle-Forming Potential

Collaborators (26)

Toshio Suda

Takeshi Masuda

Takumi Higaki

Cesar Nombela-Arrieta

Takashi Nakano

Markus G. Manz

Takayuki Yamashita

Fabienne Meier-Abt

Ken Ishii

Satoshi Tsunoda

Takaaki Akaike

Amelia Jieying Lau

Fan-Yan Wei

Masayuki Kai

Yoshikazu Hayashi

Hidenobu MIZUNO

Shuhei Koide

Junichiro Yoshimoto

Atsuo Sasaki

Shinji Fukuda

Yuichiro Arima

Emma Slack

Susumu Goyama

Tatsuya Morishima

Steffen Boettcher

Shuhei Ueda

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