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Hsin-Yao Tang

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Co-Scientific Director

The Wistar Institute

United States

Research Interests

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Professors in United States Professors in Cell Biology Cell Biology professors in United States

Recent Grants

Grant: Open

Advancing Cancer Research through Comprehensive Proteomics and Metabolomics Analyses

Open Date: 2017-09-20

Close Date: 2027-08-31

Grant: Close

Consolidated Basic Cancer Research Program

Open Date: 1978-09-01

Close Date: 2026-02-28

Articles (20)

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Collaborators (16)

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Institut Gustave Roussy

FRANCE

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Magid Abou-Gharbia

Laura H. Carnell Professor and Founding Director of Moulder Center for Drug Discovery

Temple University

UNITED STATES

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Peng Ji

Professor and Vice Chair

Northwestern University

UNITED STATES

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michela perego

Research Assistant Professor

The Wistar Institute

UNITED STATES

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IRENE BERTOLINI

The Wistar Institute

UNITED STATES

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Rui Guo

Assistant Professor

Tufts University School of Medicine

UNITED STATES

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Dajiang Guo

Research Assistant Professor

The Chinese University of Hong Kong (CUHK)

CHINA

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Assistant Professor

Northwestern University

UNITED STATES

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Hsin-Yao Tang

Research Interests

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Recent Grants

Articles (20)

PRT3789 Is a First-in-Human SMARCA2-Selective Degrader That Induces Synthetic Lethality in SMARCA4-Mutated Cancers

Aberrant Erythrocyte Rigidity in JAK2V617F Myeloproliferative Neoplasms Underlies Concurrent Thrombosis and Hemorrhage

Targeting p300 Reverses Acidic Microenvironment–Induced PARP Inhibitor Resistance

Liver Regeneration CRISPR Screen Identifies E3 Ligase NEURL1B Regulates Hepatocyte Mitosis by Destabilizing Microtubule-Organizing Centers

ATF4 coordinates amino acid and nucleotide synthesis with selective protein translation to ensure proper DNA replication timing in leukemia cells.

Nuclear export of R-loop by the DDX1 and XPO1 complex promotes senescence-associated secretory phenotype and inflammaging

Distinct associations of pioneer factor Ascl1-E12a with nucleosomes drive changes in cell fate.

Variants in glycine decarboxylase activate catabolic mechanisms of mitochondrial energy metabolism in the brain

Mitochondrial double-stranded RNA fuels pancreatic cancer growth via RIG-I/TLR3 inflammation

Immune-focused RBD nanoparticles induce cross-reactive, RBS-directed responses capable of variant-resistant SARS-CoV-2 neutralization.

Protocol for identification of protein citrullination by immunoprecipitation followed by mass spectrometry.

Targeting Interactions Between Siglec-10 and α3β1 Integrin Enhances Macrophage-Mediated Phagocytosis of Pancreatic Cancer

Ex vivo and in vivo HIV-1 latency reversal by "Mukungulu," a protein kinase C-activating African medicinal plant extract.

Parkin Induces Ubiquitination and Large Extracellular Vesicle Release of HMGB1 to Activate Antitumor Immunity

The CTLH ubiquitin ligase substrates ZMYND19 and MKLN1 negatively regulate mTORC1 at the lysosomal membrane

Combinatorial use of VHL and KEAP1 PROTACs reveals unexpected synergy and hook effect relief.

Stage-dependent dual mechanisms of MORC2 in retrotransposon silencing and sex chromosome inactivation in germ cells.

Targeted citrullination enables p53 binding to non-canonical sites.

The SHFV nsp2 and nucleocapsid proteins recruit G3BP1 to sites of viral replication, but stress granules are not induced by the infection

Dehydroglutathione, a glutathione derivative to introduce non-reversible glutathionylation.

Collaborators (16)

Catline NOBRE

Magid Abou-Gharbia

Peng Ji

michela perego

IRENE BERTOLINI

Rui Guo

Dajiang Guo

Italo Tempera

Wei Tong

Vladimir Muzykantov

Lucia Languino

Valerie Tutwiler

Stefano Rivella

Charles Abrams

Aaron Goldman

Judd Hultquist

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