Hugo de Jonge

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University lecturer

University of Pavia

Italy

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About

Hugo de Jonge is a University Lecturer at the University of Pavia, Italy. His research focuses on the fields of molecular imaging, cancer therapy, and tissue regeneration, as evidenced by his recent publications on the activity of EGFR inhibitors in lung cancer and the molecular dynamics of the MET receptor. Additionally, he explores innovative approaches to enhance cellular differentiation and energy metabolism through receptor signaling pathways.

Recent Grants

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Binding Determinants of Glycoprotein Hormone Receptors

Open Date: 2015-01-01

Close Date: 2015-12-01

Articles (13)

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2025

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2020

Collaborators (6)

Julian Heuberger

Charité - Universitätsmedizin Berlin

GERMANY

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Davide Maria Ferraris

Associate Professor

Università degli Studi del Piemonte Orientale

ITALY

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Laura Pasetto

Head of Unit

Istituto di Ricerche Farmacologiche Mario Negri

ITALY

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Bertrand-David Ségard

Chief Researcher

JAPAN

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Federico Forneris

University of Pavia

ITALY

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Gabri van der Pluijm

Associate Professor & Head of Urology Research Laboratory

Leiden University Medical Center

NETHERLANDS

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Hugo de Jonge

Research Interests

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Recent Grants

Articles (13)

Extrusion of BMP2+ surface colonocytes promotes stromal remodeling and tissue regeneration

Peptides inhibiting the assembly of monomeric human <scp>l</scp>‐lactate dehydrogenase into catalytically active homotetramer decrease the synthesis of lactate in cultured cells

Clinical and Preclinical Activity of EGFR Tyrosine Kinase Inhibitors in Non–Small-Cell Lung Cancer Harboring BRAF Class 3 Mutations

Single-molecule imaging and molecular dynamics simulations reveal early activation of the MET receptor in cells

Dimerization of kringle 1 domain from hepatocyte growth factor/scatter factor provides a potent MET receptor agonist

A novel agonist for the <scp>HGF</scp> receptor <scp>MET</scp> promotes differentiation of human pluripotent stem cells into hepatocyte‐like cells

A multimodal molecular imaging approach targeting urokinase plasminogen activator receptor for the diagnosis, resection and surveillance of urothelial cell carcinoma.

LANCL1 binds abscisic acid and stimulates glucose transport and mitochondrial respiration in muscle cells via the AMPK/PGC-1α/Sirt1 pathway

Side-by-Side Comparison of uPAR-Targeting Optical Imaging Antibodies and Antibody Fragments for Fluorescence-Guided Surgery of Solid Tumors

Harnessing the hERG1/β1 Integrin Complex via a Novel Bispecific Single-chain Antibody: An Effective Strategy against Solid Cancers

Anti-Cancer Auto-Antibodies: Roles, Applications and Open Issues

A Novel HGF/SF Receptor (MET) Agonist Transiently Delays the Disease Progression in an Amyotrophic Lateral Sclerosis Mouse Model by Promoting Neuronal Survival and Dampening the Immune Dysregulation

High Resolution Structure of Human Apolipoprotein (a) Kringle IV Type 2: Beyond the Lysine Binding Site

Collaborators (6)

Julian Heuberger

Davide Maria Ferraris

Laura Pasetto

Bertrand-David Ségard

Federico Forneris

Gabri van der Pluijm

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