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Hyo Sik Jang

Has grant

Assistant Professor

Van Andel Institute

United States

Research Interests

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Recent Grants

Grant: Close

The role of AHR in modulatingimmunotherapy response and adverse events in bladder cancer

Open Date: 2024-02-01

Close Date: 2026-01-31

Grant: Close

T32 GM007067

Open Date: 2016-08-01

Close Date: 2017-08-01

Articles (18)

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Collaborators (32)

Heng Li

Principal Investigator

Dana-Farber Cancer Institute

UNITED STATES

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Alan Boyle

Professor

University of Michigan

UNITED STATES

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Meng-Fan Huang

University of Washington

UNITED STATES

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Heer Mehta

Assistant Professor

Baylor College of Medicine

UNITED STATES

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Manu Singh

Westmead Institute for Medical Research

AUSTRALIA

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Peter Park

Harvard University

UNITED STATES

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Ye Liu

Research Scientist

Van Andel Institute

UNITED STATES

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Sheng Chih Jin

Assistant Professor

Washington University School of Medicine

UNITED STATES

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Satoshi Koyama

Associate Member

Broad Institute

UNITED STATES

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Joseph Longo

Assistant Professor of Oncology

Roswell Park Comprehensive Cancer Center

UNITED STATES

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Ting Wang

Washington University School of Medicine

UNITED STATES

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Hui Shen

Van Andel Institute

UNITED STATES

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Ian Frew

Full Professor

University Medical Center Freiburg

GERMANY

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Alexej Abyzov

Associate Professor of Biomedical Informatics

Mayo Clinic

UNITED STATES

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Samuel Aparicio

Head

CANADA

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Yonghao Liang

Washington University in St. Louis

UNITED STATES

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Tarah Ballinger

Associate Professor of Medicine

Indiana University School of Medicine

UNITED STATES

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Zhi Yu

Broad Institute

UNITED STATES

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Evan Worden

Assistant Professor

Van Andel Institute

UNITED STATES

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Sofia Bentivegna

University of Copenhagen

DENMARK

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Jakob Schmidt Jespersen

Staff scientist

Københavns Universitet

DENMARK

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Hitoshi Ohtani

Assistant Professor

Nagoya University

JAPAN

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Peter Crawford

Professor and Chief of Health Transformation and Entrepreneurship

Baylor College of Medicine

UNITED STATES

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Ryan Sheldon

Director

Van Andel Institute

UNITED STATES

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Tamara Prieto

Weill Cornell Medicine

UNITED STATES

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Samuel Preston

Van Andel Institute

UNITED STATES

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Jiyang Yu

Interim Chair

St. Jude Children's Research Hospital

UNITED STATES

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Tim Coorens

Research Group Leader

European Bioinformatics Institute

UNITED KINGDOM

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JI WON OH

Assistant Professor

Yonsei University College of Medicine

SOUTH KOREA

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Alexandra Thomas

Associate Director for Translational Science

Duke University

UNITED STATES

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Eric Ross

Research Professor

Fox Chase Cancer Center

UNITED STATES

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Junseok Park

Assistant Professor

Baylor College of Medicine

UNITED STATES

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Hyo Sik Jang

Research Interests

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Recent Grants

Articles (18)

Pharmacologic and Oncohistone Inhibition of SETD2 Converge on Genomic Instability

A phase 1 study of ASTX727 plus talazoparib in patients with triple‐negative or hormone resistant/HER2‐negative metastatic breast cancer

Bone marrow immunosuppressive states associate with survival after guadecitabine and atezolizumab therapy in HMA-R/R MDS

Tranquillyzer: A Neural Network Framework for Long-read Annotation and Demultiplexing

Retrotransposons in Bone and Joint Diseases

Streaming Structured Inference with Flash-SemiCRF

The Somatic Mosaicism across Human Tissues Network.

Dietary restriction reprograms CD8+ T cell fate to enhance anti-tumour immunity and immunotherapy responses

Interprotomer communication and functional asymmetry in H/ACA snoRNPs

Efficient activation of hundreds of LTR12C elements reveals cis-regulatory function determined by distinct epigenetic mechanisms

Epigenetic regulators of clonal hematopoiesis control CD8 T cell stemness during immunotherapy

Epigenetic therapy potentiates transposable element transcription to create tumor-enriched antigens in glioblastoma cells

H3K9me3 loss and ERVs activation as hallmarks for osteoarthritis progression and knee joint aging.

A Phase II Trial of Guadecitabine plus Atezolizumab in Metastatic Urothelial Carcinoma Progressing after Initial Immune Checkpoint Inhibitor Therapy.

Using long-read CAGE sequencing to profile cryptic-promoter-derived transcripts and their contribution to the immunopeptidome

Pan-cancer analysis identifies tumor-specific antigens derived from transposable elements

RNA mis-splicing drives viral mimicry response after DNMTi therapy in SETD2-mutant kidney cancer

Capture Methylation-Sensitive Restriction Enzyme Sequencing (Capture MRE-Seq) for Methylation Analysis of Highly Degraded DNA Samples

Collaborators (32)

Heng Li

Alan Boyle

Meng-Fan Huang

Heer Mehta

Manu Singh

Peter Park

Ye Liu

Sheng Chih Jin

Satoshi Koyama

Joseph Longo

Ting Wang

Hui Shen

Ian Frew

Alexej Abyzov

Samuel Aparicio

Yonghao Liang

Tarah Ballinger

Zhi Yu

Evan Worden

Sofia Bentivegna

Jakob Schmidt Jespersen

Hitoshi Ohtani

Peter Crawford

Ryan Sheldon

Tamara Prieto

Samuel Preston

Jiyang Yu

Tim Coorens

JI WON OH

Alexandra Thomas

Eric Ross

Junseok Park

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