Simon Arthur

Professor

University of Dundee

United Kingdom

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Professor Simon Arthur is a faculty member at the University of Dundee in the UK. His research interests encompass a range of topics including synaptic and cognitive effects of enriched experiences, protein signatures in neutrophils, and the role of inflammation in heart failure. Recent publications highlight his work on molecular mechanisms in memory enhancement, proteomic analysis of immune cells, and the impact of various compounds on macrophage function.

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2020

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2020

Collaborators (17)

James Abbott

Academic, Senior Lecturer (Teaching and Scholarship)

University of Dundee

UNITED KINGDOM

Simon Arthur

Research Interests

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Articles (22)

MSK1 is required for the experience- and ampakine-dependent enhancement of spatial reference memory and reversal learning and for the induction of Arc and BDNF

Optimizing Spectronaut Search Parameters to Improve Data Quality with Minimal Proteome Coverage Reductions in DIA Analyses of Heterogeneous Samples

Quantitative proteomics reveals tissue-specific, infection-induced and species-specific neutrophil protein signatures

Inflammation as a Therapeutic Target in Heart Failure with Preserved Ejection Fraction

MSK1 is required for the beneficial synaptic and cognitive effects of enriched experience across the lifespan

Dexamethasone impairs the expression of antimicrobial mediators in lipopolysaccharide-activated primary macrophages by inhibiting both expression and function of interferon β

CREB serine 133 is necessary for spatial cognitive flexibility and long-term potentiation

Stress signaling boosts interferon-induced gene transcription in macrophages

MSK-Mediated Phosphorylation of Histone H3 Ser28 Couples MAPK Signalling with Early Gene Induction and Cardiac Hypertrophy

Nrf2 activation reprograms macrophage intermediary metabolism and suppresses the type I interferon response

DIA label-free proteomic analysis of murine bone-marrow-derived macrophages

IL-33 induces granzyme C expression in murine mast cells via an MSK1/2-CREB-dependent pathway

TAK1 protein kinase activity is required for TLR signalling and cytokine production in myeloid cells

Salt-inducible kinase 2 regulates fibrosis during bleomycin-induced lung injury

Mitogen and Stress-activated Protein Kinase 1 Negatively Regulates Hippocampal Neurogenesis

Mitogen and Stress-Activated Kinases 1 and 2 Mediate Endothelial Dysfunction

Salt-inducible kinases are required for the IL-33–dependent secretion of cytokines and chemokines in mast cells

Generation of a chemical genetic model for JAK3

Salt inducible kinases 2 and 3 are required for thymic T cell development

The devil’s in the detail: cell-specific role of PPARγ in ILC2 activation by IL-33

Experience Recruits MSK1 to Expand the Dynamic Range of Synapses and Enhance Cognition

Loss of Mef2D function enhances TLR induced IL-10 production in macrophages

Collaborators (17)

James Abbott

Lorenzo More

Sharadha Dayalan Naidu

Mathias Müller

Faisel Khan

Naveed Akbar

Ify Mordi

Alejandro J Brenes

Pavel Kovarik

Hywel Roderick

Henry J McSorley

Graham Rena

Dylan G. Ryan

Sonia A. L. Corrêa

Wei Liu

Angus Lamond

Olaf Bergmann

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