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Ignazio Caruana

Group Leader - Scientific Research

University Hospital Würzburg

Germany

Research Interests

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Articles (20)

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2026

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2023

Collaborators (16)

Angela Rizzo

Docenti

University of Milan

ITALY

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Christoph Heuser-Loy

GERMANY

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Chiara Giordano

University of Genoa

ITALY

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Federica Conte

Ricercatore - III livello professionale

Consiglio Nazionale delle Ricerche

ITALY

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Viktoria Haug

University Hospital Frankfurt

GERMANY

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Maximilian Reichert

GERMANY

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Laura De Lellis

ITALY

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Rosalba Florio

ITALY

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Manuela Antonioli

Associate Professor

University of Rome Tor Vergata

ITALY

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Manuela Iezzi

Associate Professor

University of Chieti-Pescara

ITALY

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Biagio De Angelis

Dirigente Farmacista

Ospedale Pediatrico Bambino Gesù

ITALY

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MIRELA KUKA

Assistant Professor

Vita-Salute San Raffaele University

ITALY

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Erwan Mortier

CNRS Délégation Bretagne et Pays de Loire

FRANCE

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Antonio DI STEFANO

Full Professor

Università degli Studi Gabriele d'Annunzio Chieti e Pescara

ITALY

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Natalia Di Pietro

Associate Professor

University “G. d’Annunzio” of Chieti-Pescara

ITALY

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Paola Vacca

Head of research unit

Ospedale Pediatrico Bambino Gesù

ITALY

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Ignazio Caruana

Research Interests

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Articles (20)

Multifunctional-engineered NK cells overcome tumor immunosuppression by combining PD-L1 and HLA-E targeting and endogenous IL15 production

Autophagy supports the storage of lytic granules in human NK cells

Diet and microbiome shape small-molecule cytokinin pools in mammals

FECH, a novel metabolic target influencing CAR T-cell phenotype and function

The transmembrane IL-15 isoform expressed on human melanoma cells triggers modulatory effects on tumor progression upon stimulation with the soluble IL-15Rα chain

CD94-driven <i>in vitro</i> expansion of highly functional adaptive NKG2C<SUP>+</SUP> NKG2A<SUP>-</SUP> CD57<SUP>+</SUP> NK cells from CMV<SUP>+</SUP> healthy donors

Cytokines, and biomarkers involved in the immunomodulation of pediatric cancers

Inhibition of autophagy enhances the antitumor efficacy of T/CAR T cell against neuroblastoma

Inhibition of autophagy enhances the antitumor efficacy of T/CAR T cell against neuroblastoma (vol 44, 185, 2025)

LSD1 inhibition improves efficacy of adoptive T cell therapy by enhancing CD8+ T cell responsiveness

Disease-specific T cell receptors maintain pathogenic T helper cell responses in postinfectious Lyme arthritis.

Identification of disease-specific TCRs maintaining pathogenic T helper cell responses in postinfectious Lyme Arthritis

Transition to a mesenchymal state in neuroblastoma may be characterized by a high expression of GD2 and by the acquisition of immune escape from NK cells

CAR-T-Derived Extracellular Vesicles: A Promising Development of CAR-T Anti-Tumor Therapy

Linoleic acid potentiates CD8+ T cell metabolic fitness and antitumor immunity

The roles of different forms of IL-15 in human melanoma progression

Exploiting autophagy balance in T and NK cells as a new strategy to implement adoptive cell therapies

GD2-CART01 for Relapsed or Refractory High-Risk Neuroblastoma

Impact of Multiple Minor Histocompatibility Antigen Differences on Graft-Versus-Host Disease and Relapse Risk in Pediatric Allogeneic Hematopoietic Cell Transplantation Recipients

Should I stay or should I go? Spatio-temporal control of cellular anchorage by hematopoietic factors orchestrates tumor metastatic cascade

Collaborators (16)

Angela Rizzo

Christoph Heuser-Loy

Chiara Giordano

Federica Conte

Viktoria Haug

Maximilian Reichert

Laura De Lellis

Rosalba Florio

Manuela Antonioli

Manuela Iezzi

Biagio De Angelis

MIRELA KUKA

Erwan Mortier

Antonio DI STEFANO

Natalia Di Pietro

Paola Vacca

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