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Irena Selicharová

senior researcher

Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry

Czech Republic

Research Interests

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Professors in Biochemistry

Articles (10)

Year:

2026

Year:

2026

Year:

2026

Year:

2026

Year:

2024

Year:

2023

Year:

2023

Year:

2023

Year:

2023

Year:

2023

Collaborators (6)

Michaela Tencerova

Group leader

Czech Academy of Sciences

CZECH REPUBLIC

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Ales Marek

Institute of Organic Chemistry and Biochemistry

CZECH REPUBLIC

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Lenka Zakova

Institute of Organic Chemistry and Biochemistry

CZECH REPUBLIC

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Jakub Kaminsky

Senior researcher

Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry

CZECH REPUBLIC

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Jiri Jiracek

Group leader

Institute of Organic Chemistry and Biochemistry

CZECH REPUBLIC

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Andrzej Marek Brzozowski

Professor

University of York

UNITED KINGDOM

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Irena Selicharová

Research Interests

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Articles (10)

Vesiculin reveals the role of the <scp>IGF2</scp> C‐domain in receptor specificity within the insulin– <scp>IGF</scp> system

An engineered insulin analog with dual insulin and IGF-1 receptor agonism and distinct signaling

Conformational changes in insulin receptor illuminated by live-cell linear dichroism imaging and a FLIP biosensor

Expedient single-round selection of hyper-modified aptamer targeting insulin receptor from over-represented dually nucleobase-modified DNA libraries

Combinatorial Libraries of Bipodal Binders of the Insulin Receptor

Non-glycosylated IGF2 prohormones are more mitogenic than native IGF2

Modulation of the antagonistic properties of an insulin mimetic peptide by disulfide bridge modifications

Insulin receptor Arg717 and IGF-1 receptor Arg704 play a key role in ligand binding and in receptor activation

Recombinant Insulin-Like Growth Factor 1 Dimers: Receptor Binding Affinities and Activation Abilities

Mutations at hypothetical binding site 2 in insulin and insulin-like growth factors 1 and 2

Collaborators (6)

Michaela Tencerova

Ales Marek

Lenka Zakova

Jakub Kaminsky

Jiri Jiracek

Andrzej Marek Brzozowski

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