Sakthivel Sadayappan

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University of Cincinnati

United States

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Recent Grants

Grant: Close

Molecular and Translational Aspects of Hypertrophic Cardiomyopathy

Open Date: 2022-07-01

Close Date: 2025-06-30

Grant: Close

Molecular Mechanisms of Cardiac Arrhythmias in Patients with Compound Mutations

Open Date: 2019-07-01

Close Date: 2022-06-30

Grant: Close

American Heart Association - Summer Undergraduate Research Fellowship (AHA-SURF)

Open Date: 2019-01-01

Close Date: 2021-12-31

Articles (15)

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2024

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2023

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2023

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2022

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2022

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2022

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2021

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2021

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2021

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2021

Collaborators (19)

Weikang Ma

Research Assistant Professor

Illinois Institute of Technology

UNITED STATES

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Michael Tranter

Associate Professor

The Ohio State University Wexner Medical Center

UNITED STATES

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Ryan Boudreau

Associate Professor

The University of Iowa

UNITED STATES

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Barry London

The University of Iowa

UNITED STATES

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Fadi G. Akar

Associate Professor

Yale University

UNITED STATES

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Yanbo Fan

Associate Professor

Ohio State University

UNITED STATES

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David M. Warshaw

UNITED STATES

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Wa Du

Research Assistant Professor

The Ohio State University Wexner Medical Center

UNITED STATES

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Perwez Alam

Assistant Research Professor

University of Missouri

UNITED STATES

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Vahid Serpooshan

UNITED STATES

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Isabella Grumbach

Iowa State University

UNITED STATES

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Despina Sanoudou

Associate Professor

National and Kapodistrian University of Athens

GREECE

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David Kass

Professor, Researcher, Lab Director

Johns Hopkins University

UNITED STATES

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Francesca Stillitano

Assistant Professor

University Medical Center Groningen

NETHERLANDS

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Evangelia G. Kranias

University of Cincinnati College of Medicine

UNITED STATES

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Jared McLendon

Assistant Professor

The University of Iowa

UNITED STATES

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Bradley M Palmer

Assistant Professor

University of Vermont

UNITED STATES

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Katherine Yutzey

Professor

Cincinnati Children's Hospital Medical Center

UNITED STATES

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Brian Lin

Assistant Professor

Medical College of Wisconsin

UNITED STATES

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Sakthivel Sadayappan

Research Interests

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Recent Grants

Articles (15)

Fast myosin binding protein C knockout in skeletal muscle alters length-dependent activation and myofilament structure

The structural OFF and ON states of myosin can be decoupled from the biochemical super- and disordered-relaxed states

Dynamic changes in mitral valve extracellular matrix, tissue mechanics and function in a mouse model of Marfan syndrome

Macrophage-enriched Sectm1a promotes efficient efferocytosis to attenuate ischemia/reperfusion-induced cardiac injury

Hypertrophic cardiomyopathy in MYBPC3 carriers in aging

Multiscale characterization of left ventricle active behavior in the mouse

Myosin-binding protein C stabilizes, but is not the sole determinant of SRX myosin in cardiac muscle

Myofilament Alterations Associated with Human R14del-Phospholamban Cardiomyopathy

Knockout of Sorbin And SH3 Domain Containing 2 (Sorbs2) in Cardiomyocytes Leads to Dilated Cardiomyopathy in Mice

Depletion of skeletal muscle satellite cells attenuates pathology in muscular dystrophy

In Memoriam Tribute to Jeffrey Robbins, PhD (1950–2022)

Impaired Right Ventricular Calcium Cycling Is an Early Risk Factor in R14del-Phospholamban Arrhythmias

Upregulated Angiogenesis Is Incompetent to Rescue Dilated Cardiomyopathy Phenotype in Mice.

Mutations in myosin S2 alter cardiac myosin-binding protein-C interaction in hypertrophic cardiomyopathy in a phosphorylation-dependent manner

The C0-C1f Region of Cardiac Myosin Binding Protein-C Induces Pro-Inflammatory Responses in Fibroblasts via TLR4 Signaling

Collaborators (19)

Weikang Ma

Michael Tranter

Ryan Boudreau

Barry London

Fadi G. Akar

Yanbo Fan

David M. Warshaw

Wa Du

Perwez Alam

Vahid Serpooshan

Isabella Grumbach

Despina Sanoudou

David Kass

Francesca Stillitano

Evangelia G. Kranias

Jared McLendon

Bradley M Palmer

Katherine Yutzey

Brian Lin

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