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Jade Nunez
Associate Professor
United StatesResearch Interests
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Articles (10)
Year:
2026
Year:
2026
Year:
2026
Year:
2025
Year:
2024
Year:
2024
Year:
2024
Year:
2024
BACKGROUND AND OBJECTIVES: Although blunt cerebrovascular injuries (BCVIs) are relatively common in patients with traumatic brain injuries (TBIs), uncertainty remains regarding optimal management strategies to prevent neurological complications, morbidity, and mortality. Our objectives were to characterize common care patterns; assess the prevalence of adverse outcomes, including stroke, functional deficits, and death, by BCVI grade; and evaluate therapeutic approaches to treatment in patients with BCVI and TBI. METHODS: Patients with TBI and BCVI treated at our Level I trauma center from January 2016 to December 2020 were identified. Presenting characteristics, treatment, and outcomes were captured for univariate and multivariate analyses. RESULTS: Of 323 patients with BCVI, 145 had Biffl grade I, 91 had grade II, 49 had grade III, and 38 had grade IV injuries. Lower-grade BCVIs were more frequently managed with low-dose (81 mg) aspirin ( P < .01), although all grades were predominantly treated with high-dose (150-600 mg) aspirin ( P = .10). Patients with low-grade BCVIs had significantly fewer complications ( P < .01) and strokes ( P < .01). Most strokes occurred in the acute time frame (<24 hours), including 10/11 (90.9%) grade IV-related strokes. Higher BCVI grade portended elevated risk of stroke (grade II odds ratio [OR] 5.3, grade III OR 12.2, and grade IV OR 19.6 compared with grade I; all P < .05). The use of low- or high-dose aspirin was protective against mortality (both OR 0.1, P < .05). CONCLUSION: In patients with TBI, BCVIs impart greater risk for stroke and other associated morbidities as their severity increases. It may prove difficult to mitigate high-grade BCVI-related stroke, considering most events occur in the acute window. The paucity of late time frame strokes suggest that current management strategies do help mitigate risks.
Year:
2023
Year:
2023
Collaborators (117)
Simon Erridge
University College London
Marcus Reuterwall
Karolinska Institutet
James Glasbey
University of Birmingham
Marcello Di Martino
-
Jacobo Trebol
Profesor Asociado en Ciencias de la Salud
Universidad de Salamanca
Girolamo Geraci
Docenti di ruolo di IIa fascia
University of Palermo
Dickon Hayne
University of Western Australia
Filipe Manuel Paiva dos Santos
Assistant Professor
Nursing School of Coimbra
Kyle Kalkwarf
Assistant Professor
University of Arkansas for Medical Sciences
Matteo Marro
Azienda Ospedaliero Universitaria Città della Salute e della Scienza di Torino
Jay Doucet
Professor of Surgery / Program Director
University of California, San Diego
Mohamed Elshaer
Cambridge University Hospitals
Berta Díaz-Feijoo
Head of the Gynecology Department, Hospital Clinic Barcelona (Spain)
University of Barcelona
Alberto G Barranquero
Hospital Universitari Arnau de Vilanova
Abd Jabar Nazimi
ASSOCIATE PROFESSOR
Universiti Kebangsaan Malaysia (UKM)
Lapo BENCINI
Chief
Azienda Ospedaliero-Universitaria Maggiore della Carità
Evripidis Tokidis
University of Sheffield
Philipp Foessleitner
Medical University of Vienna
Alex Alfieri
Professor
Università della Svizzera Italiana (USI)
Sivesh K Kamarajah
University of Birmingham
Franco Lumachi
Associate professor of surgery
University of Milan, School of Medicine
Pierpaolo Sileri
Full Professor of Surgery
Università Vita Salute San Raffaele
Luca Bruschini
Chief of postgraduate school
University of Pisa
Saam Tourani
University of Melbourne
Kayani Kayani
University of Birmingham
Nolan Bruce
Assistant Professor
UAMS Medical Center
André Leite-Moreira
Assistant Professor
University of Porto
Maria Irene Bellini
Associate Professor
Sapienza University of Rome
Jasper Stijns
Vrije Universiteit Brussel
James VanDerslice
Professor
University of Utah
John Primrose
University of Southampton
Maziar Nikberg
Ass. professor and Senior Lecturer
Uppsala University
Daniele Bissacco
IRCCS Istituto Auxologico Italiano
Jia Hao Law
National University Health System
Giuseppe Palomba
Dirigente Medico in Chirurgia Generale
Federico II University Hospital
Christian Stephan Betz
Chair and Head of Department
University Medical Center Hamburg-Eppendorf
Carlos A Toro
Director of Research Operations
Icahn School of Medicine at Mount Sinai
Teofila Bueser
NIHR Senior Clinical Practitioner Researcher
King's College London
Richard McGee
Chair of Paediatrics and Child Health
Newcastle University
Stefano Piero Bernardo Cioffi
Attending surgeon
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
Awais Bokhari
Brno University of Technology
Stefano Olmi
Professor of Surgery
Vita-Salute San Raffaele University
DIETER MORALES-GARCIA
ASSOCIATE PROFESSOR OF SURGERY
University of Malaga
Maurizio Domanin
Ricercatori
University of Milan
Yolanda Carrascal
Profesor asociado
Universidad de Valladolid
Ben Arthur Marson
Clinical Associate Professor
University of Nottingham
Matteo ZOLI
Docenti di ruolo di IIa fascia
University of Bologna
Liliana Mereu
Docenti di ruolo di IIa fascia
University of Catania
Gourav Kaushal
Associate Professor
All India Institute of Medical Sciences
Tommaso Violante
Assistant Professor
University of Bologna
Susana Gonzalez Suarez
Universitat Autònoma de Barcelona (UAB)
Humberto Fenner Lyra Junior
Professor
Universidade Federal de Santa Catarina
Russell Hodgson
University of Melbourne
Ahmad Ozair
McGill University Health Centre
Michael Jenkinson
Sir John Fisher / RCSEngland Chair of Surgical Trials
University of Liverpool
Hooman Soleymani majd
Oxford University Hospitals NHS Foundation Trust
Antonios Gklavas
National and Kapodistrian University of Athens - Aretaiio Hospital
Kate Jolly
University of Birmingham
Karl-Friedrich Kowalewski
Managing Attending
University Medical Centre Mannheim
VALERIA TONINI
Professor of surgery
University of Bologna
Alfredo Conti
University of Bologna
Michele Manara
IRCCS Istituto Ortopedico Galeazzi
Xenofon Papazarkadas
University of Rochester
Hemant M Kocher
Professor of Liver and Pancreas Surgery
Queen Mary University of London
Fabio Martinelli
Ricercatori a tempo determinato
Humanitas University
Andrew Loehrer
Dartmouth-Hitchcock Medical Center
Rachel Vogel
Faculty, Associate Professor
University of Minnesota
Gianfranco Cocorullo
Docenti di ruolo di Ia fascia
University of Palermo
Jo Morrison
Honorary Associate Professor
University of Exeter
Scott Brakenridge
Professor
University of Washington
Andrea Craus-Miguel
Clinica Universidad de Navarra
Markus W. Löffler
Researcher
University Hospital Tübingen
André Lázaro
Surgeon
Hospitais da Universidade de Coimbra
SOFIA DE LA SERNA ESTEBAN
Associated Professor
Universidad Complutense de Madrid
Talal Altuwaijri
Professor
king saud university
Eduardo Domínguez-Adame Lanuza
Profesor Contratado Doctor Vinculado
Universidad de Sevilla
Georg Singer
Resident, Assistant Professor, Consultant, Associate Professor
Medical University of Graz
Santi Trimarchi
Full Professor of Vascular Surgery
Università degli Studi di Torino
Paolo Capitani
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
Saverio Tateo
Ricercatore
Università degli Studi di Enna Kore
Patrick A Coughlin
Cambridge University Hospitals NHS Foundation Trust
Adeel Ikram
Specialty Registrar Trauma & Orthopaedics, NIHR Academic Clinical Lecturer
University of Nottingham
Juan Delgado Fernandez
Hospital Universitario 12 de Octubre
Ajay Raveendranadh
Assistant Professor
Kasturba Medical College, Manipal
Mahesh Nagappa
Associate Professor
Western University
Christian Sylvest Meyhoff
Clinical Professor
Københavns Universitet
Sarah T. Menacho
University of Utah
Ioannis Tilaveridis
Associate Professor
Aristotle University of Thessaloniki
Pantelis Antonakis
Assistant Professor of Surgery
National and Kapodistrian University of Athens
Kyoichi Tomoto
The Jikei University Hospital
Dmitri Nepogodiev
NIHR Academic Clinical Lecturer in Surgical Epidemiology & Public Health
University of Birmingham
Claire M Hardie
Maternity leave
Leeds Teaching Hospitals NHS Trust
Ignacio Zapardiel
La Paz University Hospital
Aneel Bhangu
University of Birmingham
Maria P Ntalouka
Assistant Professor
University of Thessaly
Tom Abbott
NIHR Clinical Lecturer
Queen Mary University of London
Luis Joaquín García Flórez
Head, Coloproctology Section
Central University Hospital of Asturias
Eloy Espin-Basany
Chief of section
Hospital Universitari Vall d'Hebron
Maurizio Salvati
Docenti di ruolo di Ia fascia
University of Rome Tor Vergata
GIAN MARCO PRUCHER
Consultant Oral, Maxillofacial, Head and Neck Surgeon
Azienda Ospedaliero-Universitaria Maggiore della Carità
Matyas Fehervari
Imperial College London
Florian Recker
University Hospital Bonn
Khaled Dajani
Assistant Teaching Professor
University of Alberta
Matthew Seah
University of Cambridge
Anna Różańska-Walędziak
Professor
Cardinal Stefan Wyszyński University in Warsaw
Dr. med. Ahmed Abdelsamad. MD. M.Sc. MHBA
Head deputy and section head robotic surgery
-
Alanoud Alomair
Assistant Professor
princess nourah bint abdulrahman university
Thomas Freiman
Rostock University Medical Center
Julio Domenech Fernández
Profesor asociado doctor
Universidad CEU Cardenal Herrera
Funlayo Odejinmi
Barts Health NHS Trust
james catto
Professor of Urological Surgery
University of Sheffield Medical School
Alessandro Brunelli
Honorary Clinical Associate Professor
University of Leeds
Salvatore Ulisse
-
Rafael Badenes
Professor
University of Valencia
Ramesh Grandhi
University of Utah
Antonio Mario Scanu
Associate professor
Università degli Studi di Roma Tor Vergata Facoltà di Medicina e Chirurgia
Gopal Nambi
Professor
prince sattam bin abdulaziz university
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