Jan N.M. Commandeur

Associate Professor

University of Amsterdam

Netherlands

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Jan N.M. Commandeur is an Associate Professor at Vrije Universiteit Amsterdam, Netherlands. His research interests focus on toxicology, specifically the bioactivation of trichloroethylene and its effects on cellular systems, as well as the development of mechanism-based inhibitors targeting cytochrome P450 enzymes. Recent publications highlight his work on the phenotypic responses to chemical exposures and the implications for human risk assessment.

Articles (6)

Year:

2023

Year:

2023

Year:

2021

Year:

2021

Year:

2020

Year:

2020

Collaborators (3)

Paul Jennings

University of Amsterdam

NETHERLANDS

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Daan Geerke

University of Amsterdam

NETHERLANDS

View details

giada carta

University of Amsterdam

NETHERLANDS

View details

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Jan N.M. Commandeur

Research Interests

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Articles (6)

Transcriptomic-based evaluation of trichloroethylene glutathione and cysteine conjugates demonstrate phenotype-dependent stress responses in a panel of human in vitro models

Exposure to cis- and trans-regioisomers of S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2-dichlorovinyl)-glutathione result in quantitatively and qualitatively different cellular effects in RPTEC/TERT1 cells

Corrigendum to "Bioactivation of trichloroethylene to three regioisomeric glutathione conjugates by liver fractions and recombinant human glutathione transferases: Species differences and implications for human risk assessment" [Toxicol. Lett. 341 (2021) 94-106].

Bioactivation of trichloroethylene to three regioisomeric glutathione conjugates by liver fractions and recombinant human glutathione transferases: Species differences and implications for human risk assessment.

A Modified Arrhenius Approach to Thermodynamically Study Regioselectivity in Cytochrome P450-Catalyzed Substrate Conversion

Acetylene containing cyclo(L-Tyr-L-Tyr)-analogs as mechanism-based inhibitors of CYP121A1 from Mycobacterium tuberculosis.

Collaborators (3)

Paul Jennings

Daan Geerke

giada carta

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