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Jane Freeman

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Professor of Antimicrobial Resistance and Infection

University of Leeds

United Kingdom

Research Interests

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Recent Grants

Grant: Open

EVOLUTION Trial: EValuating a nOveL UTI dIagnOstic for aNtibiotic stewardship

Open Date: 2025-02-01

Close Date: 2028-07-31

Grant: Close

Clinical Evaluation and Assessment for Regulation of Diagnostic tests (CLEARED

Open Date: 2025-02-01

Close Date: 2026-01-01

Grant: Close

Efficacy of compound AJ-024 to treat initial Clostridioides difficile infection and assess the effect on gut microbiota dysbiosis and disease recurrence in a human gut model of C. difficile infection

Open Date: 2025-01-01

Close Date: 2026-06-01

Grant: Close

impact of aztreonam/avibactam and aztreonam/avibactam/ceftazidime combination therapy on the intestinal microbiota and the propensity to induce Clostridioides difficile infection in a human gut model

Open Date: 2024-02-01

Close Date: 2025-12-01

Grant: Close

Dual-site comparive evaluation of three different media for determining minimum inhibitory concnetrations of treatment antimicrobials to C. difficile to inform susceptibility testing guidelines

Open Date: 2021-06-01

Close Date: 2022-11-01

Articles (14)

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2026

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2023

Collaborators (21)

Kate Dingle

Senior Scientist

University of Oxford

UNITED KINGDOM

Jane Freeman

Research Interests

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Recent Grants

Articles (14)

Safety and efficacy of CRS3123 in adults with a primary episode or first recurrence of Clostridioides difficile infection: a phase 2, randomised, double-blind, multicentre, vancomycin-controlled study

plaTform fOr Urinary tract infection diagnostiC evAluatioN (TOUCAN): a protocol for a prospective diagnostic accuracy study of point-of-care testing in patients suspected of acute uncomplicated urinary tract infection in primary care clinics in England

Molecular clock complexities of Clostridioides difficile

Antimicrobial susceptibility testing of Clostridioides difficile: a dual-site study of three different media and three therapeutic antimicrobials

Clostridioides difficile pathogenesis and control

Current challenges in real-world management of Clostridioides difficile infection.

Clostridioides difficile canonical L,D-transpeptidases catalyze a novel type of peptidoglycan cross-links and are not required for beta-lactam resistance

Antimicrobial susceptibility in Clostridioides difficile varies according to European region and isolate source

Innovative diagnostic technologies: navigating regulatory frameworks through advances, challenges, and future prospects

Hear my voice: involving patients in Clostridioides difficile infection research

In vivo emergence of a still uncommon resistance to fidaxomicin in the urgent antimicrobial resistance threat Clostridioides difficile

Non-Toxigenic Clostridioides difficile Strain E4 (NTCD-E4) Prevents Establishment of Primary C. difficile Infection by Epidemic PCR Ribotype 027 in an In Vitro Human Gut Model

Penicillin Binding Protein Substitutions Cooccur with Fluoroquinolone Resistance in Epidemic Lineages of Multidrug-Resistant Clostridioides difficile

Decoding a cryptic mechanism of metronidazole resistance among globally disseminated fluoroquinolone-resistant Clostridioides difficile

Collaborators (21)

Kate Dingle

Mike Williamson

Jonathan Vernon

fidelma fitzpatrick

David Eyre

Andrew Timms

Mark Dickman

Benoit Guery

Thai Quan

Xavier Didelot

Philip Turner

William Spittal

Mark Lown

Kerrie Davies

Wiep Klaas Smits

Hélène Marchandin

Abiola Olaitan

darren greetham

Michael Moore

Gail Hayward

Robert Fagan

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