Jeffrey McArthur

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Conjoint Senior Lecturer

University of New South Wales Medicine & Health

Australia

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About

Jeffrey McArthur is a Conjoint Senior Lecturer at the University of New South Wales Faculty of Medicine, Australia. His research encompasses various areas including the investigation of ion channels, neuropharmacology, and the effects of peptides in pain pathways. Recently, he has contributed to articles discussing the mechanisms of analgesic conotoxins and their interactions with neuronal receptors, as well as the implications of certain calcium channel dysfunctions in migraine pathology.

Recent Grants

Grant: Close

In search of non-addictive analgesics: peripheral calcium channel targets

Open Date: 2019-04-01

Close Date: 2021-04-01

Grant: Close

Determining the Orientation of u-Conotoxin Binding in a Sodium Channel Pore

Open Date: 2009-01-01

Close Date: 2011-07-31

Articles (13)

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2023

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2023

Novel technologies for high precision and temporal resolution of cellular metabolites.

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2023

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2022

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2022

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2022

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2022

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2022

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2022

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2021

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2021

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2020

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2020

Collaborators (18)

Jason J Ivanusic

University of Melbourne

AUSTRALIA

Jeffrey McArthur

Research Interests

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About

Recent Grants

Articles (13)

A previously unrecognized superfamily of macro-conotoxins includes an inhibitor of the sensory neuron calcium channel Cav2.3

Automated Patch Clamp Screening of Amiloride and 5-N,N-Hexamethyleneamiloride Analogs Identifies 6-Iodoamiloride as a Potent Acid-Sensing Ion Channel Inhibitor

Evidence of Cytolysin A nanopore incorporation in mammalian cells assessed by a graphical user interface

<b>Analgesic α</b><b>-Conotoxin Binding Site on the Human GABA<sub>B</sub> Receptor</b>

µ-Theraphotoxin Pn3a inhibition of CaV3.3 channels reveals a novel isoform-selective drug binding site

Investigation of CACNA1I Cav3.3 Dysfunction in Hemiplegic Migraine

Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spider

Analgesic α‐conotoxins modulate native and recombinant GIRK1/2 channels via activation of GABAB receptors and reduce neuroexcitability

Pathophysiological metabolic changes associated with disease modify the proarrhythmic risk profile of drugs with potential to prolong repolarisation.

In vivo survival and differentiation of Friedreich ataxia iPSC-derived sensory neurons transplanted in the adult dorsal root ganglia.

Small-molecule mimicry hunting strategy in the imperial cone snail, <i>Conus imperialis</i>.

Molecular and Functional Characterization of Neurogenin-2 Induced Human Sensory Neurons.

Marine Toxins Targeting Kv1 Channels: Pharmacological Tools and Therapeutic Scaffolds

Collaborators (18)

Jason J Ivanusic

Volker Herzig

Ahmed Al-Sabi

Michael Kelso

Benjamin J. Buckley

B. Duygu Ozpolat

Jens Preben Morth

Marie Ranson

Rebekah Ziegman

Andrew Hung

David John Adams

LACHLAN RASH

Carsten Wloka

Lars Ellgaard

Olaf Strauss

Joshua Torres

Rocio K. Finol-Urdaneta

Anders Skov Kristensen

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