Jenna Guthmiller

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Assistant Professor

University of Colorado Health

United States

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About

Jenna Guthmiller is an Assistant Professor at the University of Colorado Health in the United States. Her research focuses on the characterization of antibodies targeting influenza, advancements in immunology, and the broader implications of antibody responses to viral infections. Recent publications include work on vaccine strategies for influenza and the cross-neutralization of SARS-CoV-2 variants. She actively addresses the importance of diversity and inclusion within STEM fields.

Recent Grants

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Investigating the development and clonal dynamics of broadly neutralizing B cells against influenza viruses

Open Date: 2021-07-01

Close Date: 2023-06-01

Grant: Close

Project Title: Role of CD138hi B cells in immunosuppression during experimental Plasmodium infection

Open Date: 2016-01-01

Close Date: 2017-12-01

Articles (17)

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UNITED STATES

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Alejandra Mendoza

Assistant professor

Scripps Research Institute

UNITED STATES

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Assistant Professor

UCSF

UNITED STATES

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Jenna Guthmiller

Research Interests

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About

Recent Grants

Articles (17)

Women in STEM becoming independent: People should feel free to be themselves and do great science

Structurally convergent antibodies derived from different vaccine strategies target the influenza virus HA anchor epitope with a subset of VH3 and VK3 genes

High-throughput synthesis and specificity characterization of natively paired influenza hemagglutinin antibodies with oPool+ display

The sweet side of H5N1 influenza virus infection

Immunity by AS03ation: The natural adjuvantage

Goldilocks Zone of Preexisting Immunity: Too Little or Too Much Suppresses Diverse Antibody Responses Against Influenza Viruses

A single mutation in dairy cow-associated H5N1 viruses increases receptor binding breadth

Broadly neutralizing antibodies target a haemagglutinin anchor epitope

Cross-Neutralization of Emerging SARS-CoV-2 Variants of Concern by Antibodies Targeting Distinct Epitopes on Spike

Hemolysis-associated phosphatidylserine exposure promotes polyclonal plasmablast differentiation.

Bridging the B Cell Gap: Novel Technologies to Study Antigen-Specific Human B Cell Responses

First exposure to the pandemic H1N1 virus induced broadly neutralizing antibodies targeting hemagglutinin head epitopes

B Cell Responses against Influenza Viruses: Short-Lived Humoral Immunity against a Life-Long Threat

Influenza hemagglutinin-specific IgA Fc-effector functionality is restricted to stalk epitopes

Extrafollicular CD4 T cell-derived IL-10 functions rapidly and transiently to support anti-Plasmodium humoral immunity

Preexisting immunity shapes distinct antibody landscapes after influenza virus infection and vaccination in humans

Polyreactive Broadly Neutralizing B cells Are Selected to Provide Defense against Pandemic Threat Influenza Viruses

Collaborators (13)

Mary Wilson

Coraline Mlynarczyk

Sean Liu

Patrick C. Wilson

Xinghong Dai

Yanbin Fu

Sophia Liu

Alejandra Mendoza

Peng Shao

Lynda Coughlan

Rahul Vijay

Noah Butler

Emily Goldberg

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