Xinghong Dai

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Assistant Professor

Case Western Reserve University

United States

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About

Xinghong Dai is an Assistant Professor at Case Western Reserve University in the United States. His research focuses on the synthesis and characterization of antibodies, especially in relation to influenza and viral immunology. Recent articles highlight his work on vaccine development, antibody specificity, and the structural basis of viral proteins, contributing to advancements in understanding viral pathogenesis and immune response.

Recent Grants

Grant: Open

Molecular basis of plasma membrane rupture in lytic cell death and its inhibition by cytoprotective agent glycine

Open Date: 2023-09-25

Close Date: 2028-08-31

Articles (9)

Year:

2025

Year:

2023

Year:

2023

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2023

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2023

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2022

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2021

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2021

Year:

2020

Collaborators (5)

Kenneth Matreyek

Assistant Professor

Case Western Reserve University

UNITED STATES

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Meng Yuan

Scripps Research Institute

UNITED STATES

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Pablo Guardado-Calvo

Université Paris Cité

FRANCE

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Collin Kieffer

Assistant Professor

University of Illinois at Urbana-Champaign

UNITED STATES

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Jenna Guthmiller

Assistant Professor

University of Colorado Health

UNITED STATES

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Xinghong Dai

Research Interests

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About

Recent Grants

Articles (9)

High-throughput synthesis and specificity characterization of natively paired influenza hemagglutinin antibodies with oPool+ display

High-throughput identification of prefusion-stabilizing mutations in SARS-CoV-2 spike.

Leveraging vaccination-induced protective antibodies to define conserved epitopes on influenza N2 neuraminidase.

Self-assembling Gn head ferritin nanoparticle vaccine provides full protection from lethal challenge of <i>Dabie bandavirus</i> in aged ferrets.

Definition of fatty acid transport protein-2 (FATP2) structure facilitates identification of small molecule inhibitors for the treatment of diabetic complications.

A yellow fever virus NS4B inhibitor not only suppresses viral replication, but also enhances the virus activation of RIG-I-like receptor-mediated innate immune response.

The epitope arrangement on flavivirus particles contributes to Mab C10’s extraordinary neutralization breadth across Zika and dengue viruses

A putative amphipathic alpha helix in hepatitis B virus small envelope protein plays a critical role in the morphogenesis of subviral particles.

Structures of capsid and capsid-associated tegument complex inside the Epstein-Barr virus.

Collaborators (5)

Kenneth Matreyek

Meng Yuan

Pablo Guardado-Calvo

Collin Kieffer

Jenna Guthmiller

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