Patricia Munroe

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Professor of Molecular Medicine

Queen Mary University of London

United Kingdom

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About

Patricia Munroe is a Professor of Molecular Medicine at Queen Mary University of London. Her research focuses on cardiovascular genetics and genomics, with recent publications addressing topics such as personalized cardiovascular treatments, hypertrophic cardiomyopathy, and the role of genomics in hypertension. She investigates the phenotypic expression of cardiac conditions and the genetic underpinnings of related diseases, contributing significantly to the field of molecular medicine.

Recent Grants

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Predicting hypertension mediated subclinical left ventricular hypertrophy using machine learning techniques

Open Date: 2020-10-05

Close Date: 2023-10-04

Grant: Close

The genetic architecture of heart rate and the electrocardiogram at rest and during exercise

Open Date: 2017-01-03

Close Date: 2020-08-01

Grant: Close

The UK DNA Banking Network

Open Date: 2007-02-01

Close Date: 2010-01-31

Grant: Close

The MRC British Genetics of Hypertension Study

Open Date: 1996-10-28

Close Date: 2008-07-30

Grant: Close

High throughput collaborative analysis of cardiovascular genes in 6000 hypertensives and 6000 controls

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Articles (20)

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2021

Collaborators (17)

Stefan Neubauer

University of Oxford

UNITED KINGDOM

Patricia Munroe

Research Interests

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About

Recent Grants

Articles (20)

Using Genomics to Develop Personalized Cardiovascular Treatments

Phenotypic expression of rare progressive cardiac conduction disease variants in the general population

Hypertrophic cardiomyopathy management: a systematic review of the clinical practice guidelines and recommendations

Harnessing the power of genomics in hypertension: tip of the iceberg?

An LGR6 frameshift variant abrogates receptor expression on select leukocyte subsets and is associated with viral infections

Promise and Peril of a Genotype‐First Approach to Mendelian Cardiovascular Disease

The ric-8b protein (resistance to inhibitors of cholinesterase 8b) is key to preserving contractile function in the adult heart

Genetic analysis of cardiac dynamic flow volumes identifies loci mapping aortic root size

Integration of genetic fine-mapping and multi-omics data reveals candidate effector genes for hypertension

Prognostic Significance of Different Ventricular Ectopic Burdens During Submaximal Exercise in Asymptomatic UK Biobank Subjects

Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.

Adverse cardiovascular magnetic resonance phenotypes are associated with greater likelihood of incident coronavirus disease 2019: findings from the UK Biobank

Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability

A Novel Two-Stage Heart Arrhythmia Ensemble Classifier

The role of resistance to inhibitors of cholinesterase 8b in the control of heart rate.

A Method to Minimise the Impact of ECG Marker Inaccuracies on the Spatial QRS-T angle: Evaluation on 1,512 Manually Annotated ECGs.

An Academic Clinician’s Road Map to Hypertension Genomics

An Academic Clinician's Road Map to Hypertension Genomics: Recent Advances and Future Directions MMXX.

No Clinically Relevant Effect of Heart Rate Increase and Heart Rate Recovery During Exercise on Cardiovascular Disease: A Mendelian Randomization Analysis.

Gut microbiome-based supervised machine learning for clinical diagnosis of inflammatory bowel diseases.

Collaborators (17)

Stefan Neubauer

Christopher Haggerty

Xueling Sim

Mark J. Caulfield

Rick Jansen

Tatijana Zemunik

Jette Bork-Jensen

Christopher Bell

Luca Biasiolli

Maciej Tomaszewski

Jesmond Dalli

Marie Spreckley

Michele Orini

Christopher Neal Foley

Rajiv Chowdhury

Andrew Morris

Alexandra Blakemore

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