Johnson Agniswamy

National Institute of Allergy and Infectious Diseases

United States

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Articles (6)

Year:

2022

Year:

2021

Year:

2021

Year:

2021

Year:

2020

Year:

2020

Collaborators (5)

Markus Germann

Prof

University of Georgia

UNITED STATES

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Masayuki Amano

Assistant professor

Kumamoto University

JAPAN

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Giovanni Gadda

University of Georgia

UNITED STATES

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Monika Yadav

Purdue University

UNITED STATES

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Robert Harrison

Professor

University of Georgia

UNITED STATES

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Johnson Agniswamy

Research Interests

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Articles (6)

Design, Synthesis and X-Ray Structural Studies of Potent HIV-1 Protease Inhibitors Containing C-4 Substituted Tricyclic Hexahydro-Furofuran Derivatives as P2 Ligands.

A Single-Point Mutation in d -Arginine Dehydrogenase Unlocks a Transient Conformational State Resulting in Altered Cofactor Reactivity

Discovery of a new flavin N5-adduct in a tyrosine to phenylalanine variant of d-Arginine dehydrogenase.

Novel HIV PR inhibitors with C4-substituted bis-THF and bis-fluoro-benzyl target the two active site mutations of highly drug resistant mutant PR<sup>S17</sup>.

Structure-Based Design of Highly Potent HIV-1 Protease Inhibitors Containing New Tricyclic Ring P2-Ligands: Design, Synthesis, Biological, and X-ray Structural Studies.

Highly drug-resistant HIV-1 protease reveals decreased intra-subunit interactions due to clusters of mutations.

Collaborators (5)

Markus Germann

Masayuki Amano

Giovanni Gadda

Monika Yadav

Robert Harrison

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