Jorge Lima

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Vice-Director and Head of R&D

IPATIMUP, Institute of Pathology and Molecular Immunology of the University of Porto

Portugal

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About

Jorge Lima is the Vice-Director and Head of R&D at Universidade do Porto Instituto de Patologia e Imunologia Molecular in Portugal. His research focuses on innovative therapies for glioblastoma, including the development of nanoparticles for targeted drug delivery, as well as the clinical impacts of hyperbaric oxygen therapy and the molecular landscape of pediatric brain tumors. He has published numerous articles addressing the biochemical and molecular mechanisms underlying tumor resistance and treatment outcomes.

Recent Grants

Grant: Close

POPCARE: Pediatric Oncology Precision Care Platform

Open Date: 2023-11-01

Close Date: 2025-11-01

Grant: Close

Unravel familial non-medullary thyroid cancer aetiology: A Genetic Orphan Disease.

Open Date: 2023-03-01

Close Date: 2024-08-31

Grant: Close

Abordagem multi-ómica em organoides ex-vivo 3D para medicina de precisão em tumores pediátricos do sistema nervoso central – OMICS.ORG

Open Date: 2022-09-01

Close Date: 2024-08-31

Grant: Close

Engineered nano-based device for glioblastoma multiforme therapy

Open Date: 2022-07-01

Close Date: 2025-06-30

Grant: Close

Ex-vivo 3D organoids for precision medicine in pediatric brain tumors - EX-BRAIN.ORG

Open Date: 2022-01-01

Close Date: 2025-01-01

Articles (10)

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2025

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2025

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2024

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2024

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2024

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2023

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2023

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2023

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PORTUGAL

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Professor Auxiliar convidado

Faculty of Medicine, University of Lisbon

PORTUGAL

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Jorge Lima

Research Interests

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Recent Grants

Articles (10)

Targeted Fluoxetine Delivery Using Folic Acid-Modified PLGA Nanoparticles for Selective Uptake by Glioblastoma Cells

Microvascular, Biochemical, and Clinical Impact of Hyperbaric Oxygen Therapy in Recalcitrant Diabetic Foot Ulcers

Chitosan-PLGA mucoadhesive nanoparticles for gemcitabine repurposing for glioblastoma therapy

Folic-Acid-Conjugated Poly (Lactic-Co-Glycolic Acid) Nanoparticles Loaded with Gallic Acid Induce Glioblastoma Cell Death by Reactive-Oxygen-Species-Induced Stress

MODL-08. PATIENT-DERIVED ORGANOIDS RECAPITULATE THE MOLECULAR LANDSCAPE OF PEDIATRIC BRAIN TUMORS

TERTmonitor—qPCR Detection of TERTp Mutations in Glioma

High VEGFA Expression Is Associated with Improved Progression-Free Survival after Bevacizumab Treatment in Recurrent Glioblastoma

Digging the intercellular crosstalk via extracellular vesicles: May exosomes be the drug delivery solution for target glioblastoma?

Kaposiform Lymphangiomatosis in a Male Adolescent: A Clinical Challenge and the Role of Genetics

Macrophage Resistance to Ionizing Radiation Exposure Is Accompanied by Decreased Cathepsin D and Increased Transferrin Receptor 1 Expression

Collaborators (9)

Daniela Martins-Mendes

Paula Soares

Rúben Fernandes

Pedro Barata

Raquel T. Lima

João Vinagre

Gonçalo C. Justino

Bruno Manadas

Carla Luís

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