Paula Soares
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About
Paula Soares is an Associate Professor at Universidade do Porto Faculdade de Medicina in Porto, Portugal. Her research encompasses various areas including the diagnosis and treatment of skin lesions, glioblastoma, and thyroid tumors. Recent articles reflect her focus on innovative medical technologies and their applications in cancer treatment and diagnostics, including the use of digital dermatoscopy, nanostructured carriers, and biomarkers in clinical practice.
Recent Grants
Grant: Close
Unravel familial non-medullary thyroid cancer aetiology: A Genetic Orphan Disease.
Open Date: 2023-03-01
Close Date: 2024-08-31
Grant: Close
CTRL+ALT+CEL: how ATRX controls an alternative program in the β-cell.
Open Date: 2022-01-01
Close Date: 2024-12-31
Grant: Close
Is thyroid gland a target of SARS-CoV-2 infection? Early identification and follow-up of thyroid dysfunction in COVID-19 patients
Open Date: 2020-07-01
Close Date: 2021-05-01
Grant: Close
As outras faces da Telomerase: olhando para além da imortalização tumoral
Open Date: 2018-07-01
Close Date: 2021-07-01
Grant: Close
Predicting patients' response to liposomal anticancer drugs: focusing on LRP1B endocytic activity
Open Date: 2018-07-01
Close Date: 2021-07-01
Articles (29)
Unraveling the Significance of DGCR8 and miRNAs in Thyroid Carcinoma
MicroRNAs (miRNAs) act as negative regulators for protein-coding gene expression impacting cell proliferation, differentiation, and survival. These miRNAs are frequently dysregulated in cancer and constitute classes of blood-based biomarkers useful for cancer detection and prognosis definition. In thyroid cancer (TC), the miRNA biogenesis pathway plays a pivotal role in thyroid gland formation, ensuring proper follicle development and hormone production. Several alterations in the miRNA biogenesis genes are reported as a causality for miRNA dysregulation. Mutations in microprocessor component genes are linked to an increased risk of developing TC; in particular, a recurrent mutation affecting DGCR8, the E518K. In this review, we explore these novel findings and resume the current state-of-the-art in miRNAs in thyroid carcinomas.
Year:
2024
Collaborators (22)
Valdemar Maximo
Assistant Professor
Faculty of Medicine of the University of Porto
Lia Rodrigues
Professora Assistente Convidada
Instituto Politécnico de Lisboa Escola Superior de Tecnologia da Saúde de Lisboa
Fernando Schmitt
Professor
Universidade do Porto Faculdade de Medicina
Carlos Eduardo de Bento Flores
University College London
Roberto De Philippis
University of Florence
Jorge Lima
Vice-Director and Head of R&D
IPATIMUP, Institute of Pathology and Molecular Immunology of the University of Porto
Maria de Fátima Gärtner
Full professor
University of Porto
Paula Tamagnini
Professora Associada
University of Porto
Raquel T. Lima
University of Porto
Rui Martins
i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto
João Vinagre
-
Luís Costa
Universidade Católica Portuguesa
COSIMO DURANTE
Associate Professor of Internal Medicine/MD, PhD
Sapienza University of Rome
Ingmar Wolff
-
José Manuel Lopes
Chief Pathologist
Centro Hospitalar Universitário do Porto
Jones Bernardes Graceli
Southern Illinois University
Ana Pestana
Junior Professor
Charité - Universitätsmedizin Berlin
Isabel Pires
Universidade de Trás-os-Montes e Alto Douro
Christian Gilfrich
-
Maria João Bugalho
Faculty of Medicine, University of Lisbon
Mafalda Pinto
Invited Professor
Escola Superior de Saúde de Santa Maria
sule canberk
Invited Professor
University of Porto
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