Jorge Valero

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Associate Professor

Universidad de Salamanca

Spain

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About

Dr. Jorge Valero is an Associate Professor at Universidad de Salamanca in Spain. His research focuses on neurobiology, particularly the roles of microglia and stem cells in neurological diseases, as well as the impacts of various signaling molecules on brain health. His recent publications explore themes such as phagocytosis dysfunction in stroke, the modulation of microglial phenotypes in Alzheimer's disease, and advancements in stem cell therapies for neurological conditions.

Recent Grants

Grant: Open

Modulating microglia-neuron crosstalk in Alzheimer’s disease

Open Date: 2023-01-01

Close Date: 2026-12-01

Grant: Close

Mitochondria as potential drivers of sex-specific microglia dysfunctional remodelling and anxiety caused by prenatal stress

Open Date: 2022-06-01

Close Date: 2023-12-01

Grant: Close

Human Neuronal Cells Differentiated from Urine-derived Stem Cells as a Platform for Personalized Medicine in Amyotrophic Lateral Sclerosis

Open Date: 2022-01-01

Close Date: 2025-01-01

Grant: Close

Regulation of prefrontal cortical synaptic function and behavior by chronic stress-induced microRNA-186-5p

Open Date: 2021-12-01

Close Date: 2024-11-01

Grant: Close

Postnatal stress, microglia, neuroplasticity and depression: the involvement of the LPA-LPA1 pathway

Open Date: 2021-10-01

Close Date: 2023-06-01

Articles (14)

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2025

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2023

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2023

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2023

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2021

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2020

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2020

Collaborators (16)

Susana Solá

Assistant Professor

Faculty of Pharmacy, University of Lisbon

PORTUGAL

Jorge Valero

Research Interests

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About

Recent Grants

Articles (14)

A bottom‐up approach identifies the antipsychotic and antineoplastic trifluoperazine and the ribose derivative deoxytubercidin as novel microglial phagocytosis inhibitors

Microglial phagocytosis dysfunction in stroke is driven by energy depletion and induction of autophagy

Recent Advances in Extracellular Vesicles in Amyotrophic Lateral Sclerosis and Emergent Perspectives

The eNOS isoform exhibits increased expression and activation in the main olfactory bulb of nNOS knock-out mice

Dual role of Apolipoprotein D as long-term instructive factor and acute signal conditioning microglial secretory and phagocytic responses

Urine-derived stem cells in neurological diseases: current state-of-the-art and future directions

Insulin-degrading enzyme (IDE) as a modulator of microglial phenotypes in the context of Alzheimer’s disease and brain aging

Immunohistochemical distribution of secretagogin in the mouse brain

A Neuron, Microglia, and Astrocyte Triple Co-culture Model to Study Alzheimer’s Disease

Susceptibility of Female Mice to the Dietary Omega-3/Omega-6 Fatty-Acid Ratio: Effects on Adult Hippocampal Neurogenesis and Glia

ATP Signaling Triggers a Pro-Neuroinflammatory Program in Hippocampal Neural Stem Cells Characterized by Overexpression of Interleukin-1β

Regulation of hippocampal postnatal and adult neurogenesis by adenosine A 2A receptor: Interaction with brain‐derived neurotrophic factor

Mitochondrial SIRT3 confers neuroprotection in Huntington’s disease by regulation of oxidative challenges and mitochondrial dynamics

Microglial phagocytosis dysfunction in the dentate gyrus is related to local neuronal activity in a genetic model of epilepsy

Collaborators (16)

Susana Solá

Flaviano Giorgini

Jitao David Zhang

Agnes NADJAR

Ana M Sebastião

David Díaz

Amanda Sierra

Paulo Oliveira

Luana Naia

GUILLERMO MARIÑO GARCÍA

Elisabete Ferreiro

Alejandro Carretero

Carla Lopes

Gonçalo Afonso

Sara Xapelli

Elena Alberdi

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