Jurgen Brem

University of Oxford

United Kingdom

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Articles (12)

Year:

2024

Year:

2024

Year:

2023

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Year:

2021

Year:

2021

Year:

2021

Year:

2021

Year:

2020

Collaborators (11)

Jon Ulf Hansen

Statens Serum Institut

DENMARK

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Chris Schofield

University of Oxford

UNITED KINGDOM

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Paula Kiuru

University of Helsinki

FINLAND

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Catherine Tooke

University of Bath

UNITED KINGDOM

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Christopher Schofield

University of Oxford

UNITED KINGDOM

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Patrick Rabe

University of Oxford

UNITED KINGDOM

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Fredrik Björkling

Københavns Universitet

DENMARK

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Madeline E. Kavanagh

Assistant Professor

Leiden University

NETHERLANDS

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Matthew Avison

University of Bristol

UNITED KINGDOM

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Marek Gniadkowski

adjunct, head of a department, associate professor (from 2005, May), professor (from 2012, Oct.)

National Medicines Institute

POLAND

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Jonathan Tyrrell

Lecturer of Biomedical Sciences & Medical Microbiology

Swansea University

UNITED KINGDOM

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Jurgen Brem

Research Interests

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Articles (12)

Biochemical and crystallographic studies of l,d-transpeptidase 2 from Mycobacterium tuberculosis with its natural monomer substrate

Cell-active small molecule inhibitors validate the SNM1A DNA repair nuclease as a cancer target

Optimized Synthesis of Indole Carboxylate Metallo-β-Lactamase Inhibitor EBL-3183

A dual covalent binder for labelling and inhibiting serine and metallo-carbapenemases

High-throughput screen with the l,d-transpeptidase LdtMt2 of Mycobacterium tuberculosis reveals novel classes of covalently reacting inhibitors

Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors

Studies on the Reactions of Biapenem with VIM Metallo β-Lactamases and the Serine β-Lactamase KPC-2

Structural Basis of Metallo-β-lactamase Inhibition by N-Sulfamoylpyrrole-2-carboxylates

Correction to “Structural Basis of Metallo-β-lactamase Inhibition by N-Sulfamoylpyrrole-2-carboxylates”

Structural Investigations of the Inhibition of Escherichia coli AmpC β-Lactamase by Diazabicyclooctanes

Design and enantioselective synthesis of 3-(α-acrylic acid) benzoxaboroles to combat carbapenemase resistance

Broad Spectrum β-Lactamase Inhibition by a Thioether Substituted Bicyclic Boronate

Collaborators (11)

Jon Ulf Hansen

Chris Schofield

Paula Kiuru

Catherine Tooke

Christopher Schofield

Patrick Rabe

Fredrik Björkling

Madeline E. Kavanagh

Matthew Avison

Marek Gniadkowski

Jonathan Tyrrell

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