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ka wan li

University of Amsterdam

Netherlands

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Research Interests

Systems Neuroscience

30%

Biochemistry

60%

Neurochemistry

40%

Protein Chemistry

40%

Neuroscience

20%

Neuroinflammation

20%

Neurodegenerative Disease

20%

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Articles15

Proteomics of the temporal cortex in semantic dementia reveals brain-region specific molecular pathology and regulation of the TDP-43-ANXA11 interactome

Article Link

Year:

2025

Multimodal beneficial effects of BNN27, a nerve growth factor synthetic mimetic, in the 5xFAD mouse model of Alzheimer’s disease

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Year:

2025

Rab10 regulates neuropeptide release by maintaining Ca2+ homeostasis and protein synthesis

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Year:

2025

Rab10 regulates neuropeptide release by maintaining Ca2+ homeostasis and protein synthesis

Article Link

Year:

2025

Power and optimal study design in iPSC-based brain disease modelling

Article Link

Year:

2023

Suspension TRAPping Filter (sTRAP) Sample Preparation for Quantitative Proteomics in the Low µg Input Range Using a Plasmid DNA Micro-Spin Column: Analysis of the Hippocampus from the 5xFAD Alzheimer’s Disease Mouse Model

Article Link

Year:

2023

Blue Native PAGE–Antibody Shift in Conjunction with Mass Spectrometry to Reveal Protein Subcomplexes: Detection of a Cerebellar α1/α6-Subunits Containing γ-Aminobutyric Acid Type A Receptor Subtype

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Year:

2023

MS-DAP Platform for Downstream Data Analysis of Label-Free Proteomics Uncovers Optimal Workflows in Benchmark Data Sets and Increased Sensitivity in Analysis of Alzheimer’s Biomarker Data

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Year:

2023

Excessive proteostasis contributes to pathology in fragile X syndrome

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Year:

2023

Protein disulfide isomerases as CSF biomarkers for the neuronal response to tau pathology

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Year:

2023

Succinate mediates inflammation-induced adrenocortical dysfunction

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Year:

2023

Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders

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Year:

2023

Brain Region Differences in α1- and α5-Subunit-Containing GABAA Receptor Proteomes Revealed with Affinity Purification and Blue Native PAGE Proteomics

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Year:

2023

Proteomics of the dentate gyrus reveals semantic dementia specific molecular pathology

Article Link

Year:

2022

Expression and Interaction Proteomics of GluA1- and GluA3-Subunit-Containing AMPARs Reveal Distinct Protein Composition

Article Link

Year:

2022

Collaborators11

Emily Osterweil

Massachusetts Institute of Technology

UNITED STATES

Hanna Lammertse

University of Amsterdam

NETHERLANDS

Jeroen van Rooij

Assistant professor

Erasmus University Rotterdam

NETHERLANDS

Ioannis Charalampopoulos

Associate Professor

University of Crete School of Medicine

GREECE

Lisa Vermunt

University of Amsterdam

NETHERLANDS

Frank Koopmans

University of Amsterdam

NETHERLANDS

Sophie van der Sluis

University of Amsterdam

NETHERLANDS

Ruud Toonen

University of Amsterdam

NETHERLANDS

Sophie J. F. Spek, van der

University of Amsterdam

NETHERLANDS

Suzanne Miedema

University of Amsterdam

NETHERLANDS

Matthijs Verhage

NETHERLANDS

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