Kai Blin

Technical University of Denmark

Denmark

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Professors in Microbiology

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Articles (12)

Year:

2024

Year:

2023

Year:

2023

Year:

2023

Year:

2023

Many microorganisms produce natural products that are frequently used in the development of medicines and crop protection agents. Genome mining has evolved into a prominent method to access this potential. antiSMASH is the most popular tool for this task. Here we present version 4 of the antiSMASH database, providing biosynthetic gene clusters detected by antiSMASH 7.1 in publicly available, dereplicated, high-quality microbial genomes via an interactive graphical user interface. In version 4, the database contains 231 534 high quality BGC regions from 592 archaeal, 35 726 bacterial and 236 fungal genomes and is available at https://antismash-db.secondarymetabolites.org/.

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Year:

2021

Year:

2021

Year:

2021

Collaborators (35)

Francesca Grisoni

Eindhoven University of Technology

NETHERLANDS

Kai Blin

Research Interests

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Articles (12)

A treasure trove of 1034 actinomycete genomes

Artificial intelligence for natural product drug discovery

antiSMASH 7.0: new and improved predictions for detection, regulation, chemical structures and visualisation

MIBiG 3.0: a community-driven effort to annotate experimentally validated biosynthetic gene clusters

SpikeSeq: A rapid, cost efficient and simple method to identify SARS-CoV-2 variants of concern by Sanger sequencing part of the spike protein gene

The antiSMASH database version 4: additional genomes and BGCs, new sequence-based searches and more

Identification of the Biosynthetic Gene Cluster for Pyracrimycin A, an Antibiotic Produced by Streptomyces sp.

ARTS-DB: a database for antibiotic resistant targets

Discovery of gargantulides B and C, new 52-membered macrolactones from Amycolatopsis sp. Complete absolute stereochemistry of the gargantulide family

Complete genome sequence of Amycolatopsis sp. CA-230715, encoding a 35-module type I polyketide synthase

Discovery and Characterization of Epemicins A and B, New 30-Membered Macrolides from Kutzneria sp. CA-103260

A Regulator Based “Semi-Targeted” Approach to Activate Silent Biosynthetic Gene Clusters

Collaborators (35)

Francesca Grisoni

Pep Charusanti

Thomas Tørring

Mads Albertsen

Omkar Mohite

Rasmus L. Marvig

Nadine Ziemert

Martin Schou Pedersen

Francisco Barona Gómez

Mehdi Beniddir

Katherine R. Duncan

Nicole Avalon

Justin van der Hooft

Wonyong Kim

Rolf Müller

Kyo Bin Kang

Laura Carroll

Thomas Yssing Michaelsen

Neha Garg

Kristina Haslinger

Jaclyn Winter

Tilmann Weber

Somayah Elsayed

Allison Walker

Thomas Ostenfeld Larsen

Robert Kalkreuter

Charlotte Held Gotfredsen

Andreas Kulik

Eric J. N. Helfrich

Mitja Maximilian Zdouc

David Ackland Tanner

Nathaniel I. Martin

Nika Sokolova

Barbara Zdrazil

William W. Metcalf

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