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Kristina Haslinger

Has grant

Scientific Staff, Associate Professor, Universitair hoofddocent

Rijksuniversiteit Groningen

Netherlands

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About

Kristina Haslinger is an Assistant Professor at Rijksuniversiteit Groningen in the Netherlands. Her research focuses on the functional diversity of polyketide synthases in fungi, as well as the biosynthesis of bioactive compounds and secondary metabolites. Recent articles include works on bioactive compounds from endophytic fungi, enzymatic steps in meroterpenoid biosynthesis, and the engineering of biosynthetic pathways.

Recent Grants

Grant: Open

FunCTion – Fungal community typification and rational design to improve plant traits

Open Date: 2025-10-01

Close Date: 2030-10-01

Grant: Open

MARMOT – Microbial biosynthetic platform for ARomatic MerOTerpenoids

Open Date: 2024-12-01

Close Date: 2029-12-01

Grant: Close

HIC-MED: Harnessing interspecies competition in microbial endophytic communities for antimicrobial discovery

Open Date: 2024-08-01

Close Date: 2026-08-01

Grant: Close

Tackling fungal infections at their roots – developing precision drugs acting on the packaging of DNA

Open Date: 2023-08-01

Close Date: 2024-08-01

Grant: Close

Deep dive into the microbiome of medicinal plants – how do microbes contribute to secondary metabolite production?

Open Date: 2022-02-01

Close Date: 2025-01-01

Articles (29)

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2020

Collaborators (50)

Christian Zimmermann

TU Wien

AUSTRIA

Kristina Haslinger

Research Interests

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About

Recent Grants

Articles (29)

Enzymatic synthesis of bioactive quinolones and (thio)coumarins by fungal type III polyketide synthases

De novo biosynthesis of alpinetin enhanced by directed evolution of 5-O-methyltransferase

Predicting Functional Diversity Within Enzyme Families: A Practical Perspective

De novo whole genome assembly of the globally invasive green shore crab Carcinus maenas (Linnaeus, 1758) via long-read Oxford Nanopore MinION sequencing

A discriminative primer design workflow enables selective metabarcoding, demonstrated using long-read sequencing of endophytic fungi

Linking antioxidant activity to strain-specific exometabolomic profiles in probiotic Lactobacillus paracasei and Lactobacillus plantarum fermentation supernatants

Predicting substrate specificity in fungal type III polyketide synthases

MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration

Unravelling the Functional Diversity of Type III Polyketide Synthases in Fungi

Unravelling the Functional Diversity of Type III Polyketide Synthases in Fungi

The endophytic fungus Cosmosporella sp. VM-42 from Vinca minor is a source of bioactive compounds with potent activity against drug-resistant bacteria

Engineering a Plant Polyketide Synthase for the Biosynthesis of Methylated Flavonoids

Discovery and Heterologous Expression of Functional 4-O-Dimethylallyl-l-tyrosine Synthases from Lichen-Forming Fungi

Jasmine scent from engineered microbes

Genome sequencing and molecular networking analysis of the wild fungus Anthostomella pinea reveal its ability to produce a diverse range of secondary metabolites

Identification and Reconstitution of the First Two Enzymatic Steps for the Biosynthesis of Bioactive Meroterpenoids from Hericium erinaceus (Lion’s Mane Mushroom)

Genome sequencing and molecular networking analysis of the wild fungus Anthostomella pinea reveal its ability to produce a diverse range of secondary metabolites

MIBiG 3.0: a community-driven effort to annotate experimentally validated biosynthetic gene clusters

Structural Characterization and Extended Substrate Scope Analysis of Two Mg2+‐Dependent O‐Methyltransferases from Bacteria**

Genomic and Metabolomic Analysis of the Endophytic Fungus Fusarium sp. VM-40 Isolated from the Medicinal Plant Vinca minor

Heterologous Naringenin Production in the Filamentous Fungus Penicillium rubens

Design and engineering of artificial biosynthetic pathways—where do we stand and where do we go?

Striving for sustainable biosynthesis: discovery, diversification, and production of antimicrobial drugs in Escherichia coli

Trendbericht Biochemie 2022

Artemisinin-Type Drugs in Tumor Cell Death: Mechanisms, Combination Treatment with Biologics and Nanoparticle Delivery

Rapid in vitro prototyping of O-methyltransferases for pathway applications in Escherichia coli

Current State and Future Directions of Genetics and Genomics of Endophytic Fungi for Bioprospecting Efforts.

Natural combinatorial genetics and prolific polyamine production enable siderophore diversification in Serratia plymuthica

Heterologous caffeic acid biosynthesis in Escherichia coli is affected by choice of tyrosine ammonia lyase and redox partners for bacterial Cytochrome P450

Collaborators (50)

Christian Zimmermann

Alexey Gurevich

Taifo Mahmud

Thomas Tørring

Rick Oerlemans

Sébastian Lequime

Shravan Dommaraju

Dongsoo Yang

Juan Pablo Gomez-Escribano

Luis C. Branco

Max Crüsemann

Paul Michael D'Agostino

Thomas Hackl

Francisco Barona Gómez

Katherine R. Duncan

Arnold J.M. Driessen

Matthew Groves

Claudio Greco

Simon Sieber

Novriyandi Hanif

Nicole Avalon

Wonyong Kim

Yit-Heng Chooi

Kyo Bin Kang

Xinyu Zhou

Eva C. Sonnenschein

Wim J. Quax

Peter Fodran

Adriano Rutz

Kai Blin

Douglas Mitchell

Sandy Schmidt

Thanh-Hau Huynh

Jaclyn Winter

Nicolau Sbaraini

Tilmann Weber

Bohdan Ostash

Cuauhtemoc Licona-Cassani

Robert Kalkreuter

Isabella PISANO

Jan Maarten van Dijl

Darren Holland

Ludek Sehnal

Eric J. N. Helfrich