Kai Tan

Has grant

Professor

University of Pennsylvania

United States

Research Interests

Explore related searches

Professors in United States Professors in Immunology Immunology professors in United States

Contact this professor

Get a free first email built on one of their papers, ready for you to edit and send yourself.

About

Dr. Kai Tan is a Professor at the University of Pennsylvania, USA. His research primarily focuses on stem cell biology and oncology, with recent articles exploring topics such as chemotherapy resistance in acute myeloid leukemia and the characterization of tumor-associated macrophages. His work also includes the development of models for tissue image segmentation and investigations into the cellular environments of bone marrow niches.

Recent Grants

Grant: Close

Comprehensive Evaluation of Immune Function in Patients Receiving Multimodal Therapy for High-Risk Neuroblastoma

Open Date: 2020-10-01

Close Date: 2021-09-01

Grant: Close

Center for Developmental Mapping of Heart and Bone Tissues

Open Date: 2020-09-01

Close Date: 2022-08-31

Grant: Close

Towards rational design of combination therapeutic targets

Open Date: 2020-06-01

Close Date: 2025-05-31

Grant: Close

Understanding the cellular and molecular basis of Chimeric Antigen Receptor T-cell therapy resistance

Open Date: 2020-05-01

Close Date: 2023-04-30

Grant: Close

Center for pediatric tumor cell atlas

Open Date: 2018-09-30

Close Date: 2023-08-31

Articles (20)

Year:

2025

Year:

2025

Year:

2025

Year:

2025

Year:

2024

Year:

2024

Year:

2024

Year:

2024

Year:

2024

Year:

2024

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Year:

2022

Year:

2021

Year:

2021

Year:

2021

Year:

2021

Year:

2021

Collaborators (21)

Hua Huang

University of Pennsylvania

UNITED STATES

Kai Tan

Research Interests

Explore related searches

Contact this professor

About

Recent Grants

Articles (20)

Native stem cell transcriptional circuits define cardinal features of high-risk leukemia

CelloType: a unified model for segmentation and classification of tissue images

GATA2 links stemness to chemotherapy resistance in acute myeloid leukemia.

Targeting Senescent Stemlike Subpopulations in Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia.

Identification and Characterization of Chemotherapy-Resistant High-Risk Neuroblastoma Persister Cells.

A multiomic atlas identifies a treatment-resistant, bone marrow progenitor-like cell population in T cell acute lymphoblastic leukemia.

An iron-rich subset of macrophages promotes tumor growth through a Bach1-Ednrb axis.

The genomic basis of childhood T-lineage acute lymphoblastic leukaemia.

Mapping the cellular biogeography of human bone marrow niches using single-cell transcriptomics and proteomic imaging.

Single-cell multiomics guided mechanistic understanding of Fontan-associated liver disease.

Epigenetic state determines inflammatory sensing in neuroblastoma

MITI minimum information guidelines for highly multiplexed tissue images.

Endothelial MEKK3-KLF2/4 signaling integrates inflammatory and hemodynamic signals during definitive hematopoiesis

B cell targeting in CAR T cell therapy: Side effect or driver of CAR T cell function?

Decade-long leukaemia remissions with persistence of CD4<sup>+</sup> CAR T cells.

Efficient hemogenic endothelial cell specification by RUNX1 is dependent on baseline chromatin accessibility of RUNX1-regulated TGFβ target genes

Kikuchi-Fujimoto disease is mediated by an aberrant type I interferon response.

Network Analysis Reveals Synergistic Genetic Dependencies for Rational Combination Therapy in Philadelphia Chromosome-like Acute Lymphoblastic Leukemia.

CytoTalk: De novo construction of signal transduction networks using single-cell transcriptomic data.

Integrative bulk and single-cell profiling of pre-manufacture T-cell populations reveals factors mediating long-term persistence of CAR T-cell therapy.

Collaborators (21)

Hua Huang

Melike Lakadamyali

Derek Sung

Garry Nolan

Gregory J. Baker

Russell J.H. Ryan

Peter Bankhead

Shahin Rafii

Markus Daniel Herrmann

David Teachey

Adam Wolpaw

Wenbao Yu

Michael Angelo

Jan Joseph Melenhorst

Samouil Farhi

Daniel Abravanel

Warren Kibbe

Liming Pei

Marie Arsenian Henriksson

Damir Sudar

Jeremy Muhlich

Make your next move.