Katharina Richter profile picture

Katharina Richter

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University of Adelaide
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Australia

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Recent Grants

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Maximising the effectiveness of antimicrobial treatments for infection control after surgery

Open Date: 2019-01-01

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Grant: Close

Improving clinical outcomes of antimicrobial resistant infections with a drug-free intervention

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Positions (1)

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Adelaide University

Adelaide University

Fully Funded PhD Scholarship in Bacterial Sterilisation Using Quantum Light at Adelaide University

PhD scholarship opportunity at Adelaide University through the ARC Training Centre for Current and Emergent Quantum Technologies (QuTech) . The highlighted project is Bacterial Sterilisation Using Quantum Light , supervised in the QuTech program and linked to real-world healthcare innovation with Lindo . The research sits at the intersection of physics , biology , biomedical engineering , medical science , and photonics , with a focus on antimicrobial blue light and chemical-free disinfection of hospital plumbing. The project aims to develop the Lindo Drain , a retrofittable insert that continuously disinfects hospital sink drains and reduces antibiotic-resistant bacteria. The post describes the work as a scalable solution with strong translational impact, targeting infection control in healthcare settings. This is a fully funded PhD scholarship. The scholarship information on the QuTech site states a stipend of $36,161 per year (indexed annually) plus a $10,000 top-up per year , for up to 3.5 years . International applicants should note that mandatory Overseas Student Health Cover is not covered by the scholarship. Eligibility: Australian citizens or permanent residents are eligible, and international students who can be accepted as HDR candidates at the host universities may also apply. For this specific project, domestic AU/NZ applicants are preferred, though strong international applicants are welcome. Applicants should have a strong research background and provide academic documents plus evidence of English language proficiency. How to apply: Submit an expression of interest by email to [email protected] with the project number 3.2 in the subject line. Include transcripts, degree parchments, translations of non-English documents, English proficiency evidence, and a CV. Short-listed candidates will be interviewed and then invited to submit a formal application for admission. Application window: Applications opened 8 October 2024 and are open until filled.

Articles (9)

Efficacy of Plasma-Treated Water against Salmonella Typhimurium: Antibacterial Activity, Inhibition of Invasion, and Biofilm Disruption

Plasma-treated water (PTW) has emerged as a potential sanitizing agent. This study evaluated antibacterial activity, inhibition of invasion, and biofilm disruption effects of PTW against Salmonella Typhimurium. Minimum inhibitory concentrations (MICs) and minimum bactericidal concentrations (MBCs) were determined for different PTW types. Time-kill assays were conducted to assess bactericidal effects, while polarized Caco-2 cells were used to evaluate invasion inhibition. Biofilm formation and cell viability were examined following PTW treatment using Salmonella Typhimurium isolates, while biofilm disruption and regrowth prevention were investigated using the Bioflux system. PTW exhibited antibacterial activity against all Salmonella Typhimurium isolates, with MICs of 25% for PTW1 and PTW2, and 50% for PTW3, PTW4, and PTW5. MBCs of 50% in media were observed for all PTW types. Undiluted PTW1 and PTW2 showed the highest bactericidal capacity, significantly reduced Salmonella viability, and completely inhibited bacterial invasion, while PTW3 and PTW5 also showed significant invasion reduction. Bioflux experiments confirmed the eradication of biofilms by PTW1 and PTW2, with no regrowth observed 72 h after PTW was removed. PTW demonstrated significant antibacterial activity, inhibition of invasion, biofilm disruption, and reduction of bacterial viability against Salmonella Typhimurium. This highlights PTW’s potential as an effective sanitizer for reducing Salmonella contaminations.

Year:

2023

Collaborators (4)

Honghua Hu

Macquarie University

AUSTRALIA

Bastiaan Krom

University of Amsterdam

NETHERLANDS

Anita Jacombs

Senior Lecturer - Clinician

University of Sydney

AUSTRALIA

Renjy Nelson

Associate Professor

University of Adelaide

AUSTRALIA
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