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Kathryn J Wicht

Lecturer and Research Group Leader

University of Cape Town

South Africa

Research Interests

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Professors in Biochemistry

Articles (18)

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2026

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2026

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2026

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2024

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2023

Collaborators (7)

Clinton Veale

Associate Professor

University of Cape Town

SOUTH AFRICA

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Sandeep Ghorpade

Head of Drug Discovery

University of Cape Town

SOUTH AFRICA

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Lyn-Marie Birkholtz

Professor and Research Chair

Stellenbosch University

SOUTH AFRICA

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Marcus Lee

Professor

University of Dundee

UNITED KINGDOM

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Flore Nardella

FRANCE

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Angela Corona

Assistant Professor

University of Cagliari

ITALY

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Elizabeth Winzeler

Professor

University of California, San Diego

UNITED STATES

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Kathryn J Wicht

Research Interests

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Articles (18)

PCA-mapping and machine learning identify multiple chemotypes with antiplasmodial, β-haematin and haemozoin formation inhibition activity

The Human Chk1 Inhibitor CHIR-124 Shows Multistage Activity against the Human Malaria Parasite <i>Plasmodium falciparum</i> via Polypharmacological Inhibition of <i>Pf</i> Ark1 and Hemozoin Formation

Using Unbiased Chemical Proteomics Approaches to Explore the Target Landscape of the Resistance Refractory 7-Azaindole MMV022224 in <i> <i>Plasmodium falciparum</i> </i>

Infectious Diseases Research in the Global South: Treatments and Treatment Failures

New thinking for the next generation of antimalarials

Effect of Stereochemistry on the Antiplasmodial Activity and Metabolomic Profile of Novel Tadalafil Analogues

Ferrocenyl Quinoline-Benzimidazole Hybrids: A Multistage Strategy to Combat Drug-Resistant Malaria

Synthesis and SAR Studies of Acyl-Thiourea Platinum(II) Complexes Yield Analogs with Dual-Stage Antiplasmodium Activity

The ATM Kinase Inhibitor AZD0156 Is a Potent Inhibitor of Plasmodium Phosphatidylinositol 4-Kinase (PI4Kβ) and Is an Attractive Candidate for Medicinal Chemistry Optimization Against Malaria

Chemistry as a Catalyst for Transforming the Health and Wealth of South Africa

Repositioning a human kinase platelet-derived growth factor receptor alpha type II inhibitor for malaria and inhibition of hemozoin formation

Heme processing in the malaria parasite, Plasmodium falciparum: a time-dependent basal-level analysis

2,8-Disubstituted-1,5-naphthyridines as Dual Inhibitors of <i>Plasmodium falciparum</i> Phosphatidylinositol-4-kinase and Hemozoin Formation with <i>In Vivo</i> Efficacy.

Call for Papers: Infectious Diseases Research in the Global South: Treatments and Treatment Failures

hERG, Plasmodium Life Cycle, and Cross Resistance Profiling of New Azabenzimidazole Analogues of Astemizole

Drug discovery in Africa tackles zoonotic and related infections

Pyrido-Dibemequine Metabolites Exhibit Improved Druglike Features, Inhibit Hemozoin Formation in Plasmodium falciparum, and Synergize with Clinical Antimalarials

Identifying inhibitors of β-haematin formation with activity against chloroquine-resistant Plasmodium falciparum malaria parasites via virtual screening approaches.

Collaborators (7)

Clinton Veale

Sandeep Ghorpade

Lyn-Marie Birkholtz

Marcus Lee

Flore Nardella

Angela Corona

Elizabeth Winzeler

Make your next move.

Kathryn J Wicht

Research Interests

Make your next move.

Explore related searches

Articles (18)

PCA-mapping and machine learning identify multiple chemotypes with antiplasmodial, β-haematin and haemozoin formation inhibition activity

The Human Chk1 Inhibitor CHIR-124 Shows Multistage Activity against the Human Malaria Parasite <i>Plasmodium falciparum</i> via Polypharmacological Inhibition of <i>Pf</i> Ark1 and Hemozoin Formation

Using Unbiased Chemical Proteomics Approaches to Explore the Target Landscape of the Resistance Refractory 7-Azaindole MMV022224 in <i> <i>Plasmodium falciparum</i> </i>

Infectious Diseases Research in the Global South: Treatments and Treatment Failures

New thinking for the next generation of antimalarials

Effect of Stereochemistry on the Antiplasmodial Activity and Metabolomic Profile of Novel Tadalafil Analogues

Ferrocenyl Quinoline-Benzimidazole Hybrids: A Multistage Strategy to Combat Drug-Resistant Malaria

Synthesis and SAR Studies of Acyl-Thiourea Platinum(II) Complexes Yield Analogs with Dual-Stage Antiplasmodium Activity

The ATM Kinase Inhibitor AZD0156 Is a Potent Inhibitor of Plasmodium Phosphatidylinositol 4-Kinase (PI4Kβ) and Is an Attractive Candidate for Medicinal Chemistry Optimization Against Malaria

Chemistry as a Catalyst for Transforming the Health and Wealth of South Africa

Repositioning a human kinase platelet-derived growth factor receptor alpha type II inhibitor for malaria and inhibition of hemozoin formation

Heme processing in the malaria parasite, Plasmodium falciparum: a time-dependent basal-level analysis

2,8-Disubstituted-1,5-naphthyridines as Dual Inhibitors of &lt;i&gt;Plasmodium falciparum&lt;/i&gt; Phosphatidylinositol-4-kinase and Hemozoin Formation with &lt;i&gt;In Vivo&lt;/i&gt; Efficacy.

Call for Papers: Infectious Diseases Research in the Global South: Treatments and Treatment Failures

hERG, Plasmodium Life Cycle, and Cross Resistance Profiling of New Azabenzimidazole Analogues of Astemizole

Drug discovery in Africa tackles zoonotic and related infections

Pyrido-Dibemequine Metabolites Exhibit Improved Druglike Features, Inhibit Hemozoin Formation in Plasmodium falciparum, and Synergize with Clinical Antimalarials

Identifying inhibitors of β-haematin formation with activity against chloroquine-resistant Plasmodium falciparum malaria parasites via virtual screening approaches.

Collaborators (7)

Clinton Veale

Sandeep Ghorpade

Lyn-Marie Birkholtz

Marcus Lee

Flore Nardella

Angela Corona

Elizabeth Winzeler

Make your next move.

2,8-Disubstituted-1,5-naphthyridines as Dual Inhibitors of <i>Plasmodium falciparum</i> Phosphatidylinositol-4-kinase and Hemozoin Formation with <i>In Vivo</i> Efficacy.