Marcus Lee

Wellcome Sanger Institute

United Kingdom

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Articles (20)

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2025

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2025

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2025

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2022

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2022

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2021

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2021

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2020

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2020

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2020

Collaborators (12)

Kely Rubiano

Research technician

Columbia University

UNITED STATES

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Tina Skinner-Adams

Associate Professor

Griffith University

AUSTRALIA

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Alejandro Marin-Menendez

Maladies Infectieuses et Vecteurs : Ecologie Génétique Evolution et Contrôle

FRANCE

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Gerbrand van der Heden van Noort

Assistant professor (Principal Investigator)

Leiden University Medical Center

NETHERLANDS

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Brad Sleebs

Laboratory Head

Walter and Eliza Hall Institute of Medical Research

AUSTRALIA

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David B Ascher

University of Queensland

AUSTRALIA

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Simon Cobbold

Walter and Eliza Hall Institute of Medical Research

AUSTRALIA

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Pedro Cravo

Universidade de Aveiro

PORTUGAL

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Duangkamon Loesbanluechai

University of Glasgow

UNITED KINGDOM

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Beatriz Baragaña

Academic, Principal Investigator/Senior Lecturer (Teaching and Research)

University of Dundee

UNITED KINGDOM

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Sachel Mok

Assistant Professor of Medical Sciences

Columbia University Irving Medical Center

UNITED STATES

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Elizabeth Winzeler

Professor

University of California, San Diego

UNITED STATES

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Marcus Lee

Research Interests

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Articles (20)

Drug resistance–associated mutations in Plasmodium UBP-1 disrupt its essential deubiquitinating activity

Optimization and Characterization of N-Acetamide Indoles as Antimalarials That Target PfATP4.

Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining

Quinoxaline-based anti-schistosomal compounds have potent anti-plasmodial activity

YAT2150 is irresistible in Plasmodium falciparum and active against Plasmodium vivax and Leishmania clinical isolates

A novel 4-aminoquinoline chemotype with multistage antimalarial activity and lack of cross-resistance with PfCRT and PfMDR1 mutants

Systematic in vitro evolution in &lt;i&gt;Plasmodium falciparum&lt;/i&gt; reveals key determinants of drug resistance

β-Carboline-3-carboxamide Antimalarials: Structure-Activity Relationship, ADME-Tox Studies, and Resistance Profiling.

2,8-Disubstituted-1,5-naphthyridines as Dual Inhibitors of <i>Plasmodium falciparum</i> Phosphatidylinositol-4-kinase and Hemozoin Formation with <i>In Vivo</i> Efficacy.

Acute response to pathogens in the early human placenta at single-cell resolution.

A transcriptional switch controls sex determination in Plasmodium falciparum

Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention

Barcoding Genetically Distinct Plasmodium falciparum Strains for Comparative Assessment of Fitness and Antimalarial Drug Resistance

MalDA, Accelerating Malaria Drug Discovery

PfMFR3: A Multidrug-Resistant Modulator in Plasmodium falciparum

Lumefantrine attenuates Plasmodium falciparum artemisinin resistance during the early ring stage.

Scientists on a RAMPAGE to find apicomplexan transcription start sites

Inhibition of Resistance-Refractory P. falciparum Kinase PKG Delivers Prophylactic, Blood Stage, and Transmission-Blocking Antiplasmodial Activity

The Key Glycolytic Enzyme Phosphofructokinase Is Involved in Resistance to Antiplasmodial Glycosides.

Insights into the intracellular localization, protein associations and artemisinin resistance properties of Plasmodium falciparum K13.

Collaborators (12)

Kely Rubiano

Tina Skinner-Adams

Alejandro Marin-Menendez

Gerbrand van der Heden van Noort

Brad Sleebs

David B Ascher

Simon Cobbold

Pedro Cravo

Duangkamon Loesbanluechai

Beatriz Baragaña

Sachel Mok

Elizabeth Winzeler

Make your next move.

Marcus Lee

Research Interests

Explore related searches

Contact this professor

Articles (20)

Drug resistance–associated mutations in Plasmodium UBP-1 disrupt its essential deubiquitinating activity

Optimization and Characterization of N-Acetamide Indoles as Antimalarials That Target PfATP4.

Revisiting the Plasmodium falciparum druggable genome using predicted structures and data mining

Quinoxaline-based anti-schistosomal compounds have potent anti-plasmodial activity

YAT2150 is irresistible in Plasmodium falciparum and active against Plasmodium vivax and Leishmania clinical isolates

A novel 4-aminoquinoline chemotype with multistage antimalarial activity and lack of cross-resistance with PfCRT and PfMDR1 mutants

Systematic in vitro evolution in &amp;lt;i&amp;gt;Plasmodium falciparum&amp;lt;/i&amp;gt; reveals key determinants of drug resistance

β-Carboline-3-carboxamide Antimalarials: Structure-Activity Relationship, ADME-Tox Studies, and Resistance Profiling.

2,8-Disubstituted-1,5-naphthyridines as Dual Inhibitors of &lt;i&gt;Plasmodium falciparum&lt;/i&gt; Phosphatidylinositol-4-kinase and Hemozoin Formation with &lt;i&gt;In Vivo&lt;/i&gt; Efficacy.

Acute response to pathogens in the early human placenta at single-cell resolution.

A transcriptional switch controls sex determination in Plasmodium falciparum

Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention

Barcoding Genetically Distinct Plasmodium falciparum Strains for Comparative Assessment of Fitness and Antimalarial Drug Resistance

MalDA, Accelerating Malaria Drug Discovery

PfMFR3: A Multidrug-Resistant Modulator in Plasmodium falciparum

Lumefantrine attenuates Plasmodium falciparum artemisinin resistance during the early ring stage.

Scientists on a RAMPAGE to find apicomplexan transcription start sites

Inhibition of Resistance-Refractory P. falciparum Kinase PKG Delivers Prophylactic, Blood Stage, and Transmission-Blocking Antiplasmodial Activity

The Key Glycolytic Enzyme Phosphofructokinase Is Involved in Resistance to Antiplasmodial Glycosides.

Insights into the intracellular localization, protein associations and artemisinin resistance properties of Plasmodium falciparum K13.

Collaborators (12)

Kely Rubiano

Tina Skinner-Adams

Alejandro Marin-Menendez

Gerbrand van der Heden van Noort

Brad Sleebs

David B Ascher

Simon Cobbold

Pedro Cravo

Duangkamon Loesbanluechai

Beatriz Baragaña

Sachel Mok

Elizabeth Winzeler

Make your next move.

Systematic in vitro evolution in <i>Plasmodium falciparum</i> reveals key determinants of drug resistance

2,8-Disubstituted-1,5-naphthyridines as Dual Inhibitors of <i>Plasmodium falciparum</i> Phosphatidylinositol-4-kinase and Hemozoin Formation with <i>In Vivo</i> Efficacy.