Kenneth Matreyek

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Assistant Professor

Case Western Reserve University

United States

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Recent Grants

Grant: Close

Recombinant DNA technologies for multiplex genetic assays in human cells

Open Date: 2021-08-01

Close Date: 2026-05-31

Grant: Close

Multiplex discovery of synthetic host-protein combinations that inhibit HIV

Open Date: 2020-11-18

Close Date: 2022-10-31

Grant: Close

Massively Parallel Mutational Analyses of Viral Neutralization Mechanisms Against Human Restriction Factors

Open Date: 2019-08-07

Close Date: 2021-07-31

Grant: Close

Massively Parallel Mutational Analyses of Viral Neutralization Mechanisms Against Human Restriction Factors

Open Date: 2019-08-07

Close Date: 2021-07-31

Grant: Close

Comprehensive Interpretation of Tumor Suppressor Variation in Cancer

Open Date: 2016-01-01

Close Date: 2018-12-01

Articles (10)

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2023

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2022

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2022

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2022

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2022

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2021

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2021

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2021

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2020

Year:

2020

Collaborators (11)

Jesse Bloom

Fred Hutchinson Cancer Research Center

UNITED STATES

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University of Minnesota

UNITED STATES

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nidhi shukla

UNITED STATES

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Kenneth Matreyek

Research Interests

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Contact this professor

Recent Grants

Articles (10)

High-throughput identification of prefusion-stabilizing mutations in SARS-CoV-2 spike.

Receptor-Binding Domain (RBD) Antibodies Contribute More to SARS-CoV-2 Neutralization When Target Cells Express High Levels of ACE2

Probing the biophysical constraints of SARS-CoV-2 spike N-terminal domain using deep mutational scanning

Expanded ACE2 dependencies of diverse SARS-like coronavirus receptor binding domains

Shifting mutational constraints in the SARS-CoV-2 receptor-binding domain during viral evolution.

Probing ion channel functional architecture and domain recombination compatibility by massively parallel domain insertion profiling

Mutants of human ACE2 differentially promote SARS-CoV and SARS-CoV-2 spike mediated infection

Integrating thousands of PTEN variant activity and abundance measurements reveals variant subgroups and new dominant negatives in cancers

MHC class II transactivator CIITA induces cell resistance to Ebola virus and SARS-like coronaviruses

Multiplexed measurement of variant abundance and activity reveals VKOR topology, active site and human variant impact.

Collaborators (11)

Jesse Bloom

Meng Yuan

Vincenzo Carnevale

Xinghong Dai

Collin Kieffer

Nicholas Wu

Willow Coyote-Maestas

Juan Manuel Carreno Quiroz

Douglas Fowler

Daniel Schmidt

nidhi shukla

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