Kensuke Miyake

Project Asoociate Professor

Tokyo Medical and Dental University

Japan

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Kensuke Miyake is a Project Associate Professor at Tokyo Medical and Dental University in Japan. His research focuses on the roles of basophils and inflammatory responses in allergic conditions and skin disorders, as highlighted in his recent articles. Notable topics include the involvement of basophils in the resolution of acute respiratory distress syndrome and their protective role in skin barrier function recovery. He has also explored the interactions between basophils and macrophages in atopic dermatitis and other inflammatory responses.

Kensuke Miyake

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Articles (21)

Emerging roles of basophils in the resolution of the acute respiratory distress syndrome

IL-33-primed NLRP3 inflammasome in basophils drives IL-1β production and initiates atopic dermatitis inflammation

Tristetraprolin-mediated mRNA destabilization regulates basophil inflammatory responses

PD-L1- and IL-4-expressing basophils promote pathogenic accumulation of T follicular helper cells in lupus.

Cutaneous basophil infiltration in atopic dermatitis is associated with abundant epidermal infiltration of helper T cells: A preliminary retrospective study

Basophils Play a Protective Role in the Recovery of Skin Barrier Function from Mechanical Injury in Mice

Topical Application of a PDE4 Inhibitor Ameliorates Atopic Dermatitis through Inhibition of Basophil IL-4 Production

Single-cell transcriptomics identifies the differentiation trajectory from inflammatory monocytes to pro-resolving macrophages in a mouse skin allergy model

Basophils are important for the development of allergic skin inflammation.

Stress-experienced monocytes/macrophages lose anti-inflammatory function via β2-adrenergic receptor in skin allergic inflammation.

Single cell transcriptomics clarifies the basophil differentiation trajectory and identifies pre-basophils upstream of mature basophils

An IL-4 signalling axis in bone marrow drives pro-tumorigenic myelopoiesis.

Role of Basophils in a Broad Spectrum of Disorders

E-cadherin is regulated by GATA-2 and marks the early commitment of mouse hematopoietic progenitors to the basophil and mast cell fates.

Basophils, a neglected minority in the immune system, have come into the limelight at last.

Basophils and their effector molecules in allergic disorders

The Role of Trogocytosis in the Modulation of Immune Cell Functions

Tolerogenic properties of CD206+ macrophages appeared in the sublingual mucosa after repeated antigen-painting.

The role of basophils in acquired protective immunity to tick infestation.

Immunobiology of Acquired Resistance to Ticks.

Skin‐infiltrating basophils promote atopic dermatitis‐like inflammation via IL‐4 production in mice

Collaborators (10)

Shigenori Nagai

Hajime Karasuyama

Timm Schroeder

Pauline Hamon

Nelson LaMarche

Miyuki Azuma

Naoko Okiyama

Padraic Fallon

Clotilde Hennequin

Atsushi Fujimura

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