Lee T. Gettler

Objectives Refugees seeking safety across international borders are often exposed to a wide breadth of psychosocially stressful experiences that may fracture existing sources of social support and impair the generation of new social relationships, with implications for their long‐term health and resilience. Using data from recently settled refugees in two asylum centers in Serbia, we examined the associations between social support, mental health, and physiological markers. Methods In this mixed‐method study of refugees (age 18–50 years, n = 76), we collected key socio‐demographic information and conducted semi‐structured interviews about refugees' journey and stay in Serbia, trauma/loss, and their sources of social support. We also collected self‐reported measures of mental well‐being as well as physiological markers relevant to repeated exposure to chronic psychosocial stress (fingernail cortisol and dried blood spots for analysis of Epstein–Barr virus [EBV] antibody titers). Results We found that refugees with longer journeys reported lower social support than those with shorter journeys. Refugees with lower social support reported poorer mental well‐being, greater PTSD‐related symptoms, and higher recent perceived stress than those with higher social support. We also observed that refugees with lower social support and higher recent stress, respectively, tended to exhibit higher fingernail cortisol levels. However, we did not observe comparable patterns linking EBV antibodies with psychosocial functioning. Conclusion Our cross‐sectional findings are consistent with the notion that social support is likely to be a critical component in effective interventions aimed at mitigating the adverse health effects of relocation‐related illnesses and poor social functioning as they await resettlement.