Lyle Ostrow

Associate Professor

Temple University

United States

Research Interests

Explore related searches

Professors in United States Professors in Medical Science Medical Science professors in United States

Contact this professor

Get a free first email built on one of their papers, ready for you to edit and send yourself.

About

Dr. Lyle Ostrow is an Associate Professor at Temple University, located in the United States. His research primarily focuses on amyotrophic lateral sclerosis (ALS) and related neurodegenerative disorders, with recent publications addressing topics such as dysarthria assessment, genetic risk management, and the immune response in ALS. He is involved in advancing clinical practice through the integration of AI technologies and precision medicine approaches.

Articles (22)

Year:

2025

Year:

2025

Year:

2025

Year:

2025

Year:

2025

Year:

2025

Year:

2024

Year:

2024

Year:

2024

Year:

2024

Year:

2024

Year:

2024

Year:

2023

Year:

2023

Year:

2023

Year:

2022

Year:

2021

Year:

2021

Year:

2021

Year:

2021

Year:

2020

Year:

2020

Collaborators (30)

Ernest Fraenkel

Massachusetts Institute of Technology

UNITED STATES

Lyle Ostrow

Research Interests

Explore related searches

Contact this professor

About

Articles (22)

Clinical assessment and interpretation of dysarthria in ALS using attention based deep learning AI models

Guidance for clinical management of pathogenic variant carriers at elevated genetic risk for ALS/FTD

Immune-related encephalitis after immune checkpoint inhibitor therapy

Listener effort measures clinically meaningful change of dysarthria in amyotrophic lateral sclerosis

Reliable monitoring of respiratory function with home spirometry in people living with amyotrophic lateral sclerosis

Single-cell transcriptomic landscape of the neuroimmune compartment in amyotrophic lateral sclerosis brain and spinal cord

ALSUntangled #75: Portable neuromodulation stimulator therapy

Distinct transcriptomic profile of satellite cells contributes to preservation of neuromuscular junctions in extraocular muscles of ALS mice

Distinct transcriptomic profile of satellite cells contributes to preservation of neuromuscular junctions in extraocular muscles of ALS mice

Biomarker Qualification for Neurofilament Light Chain in Amyotrophic Lateral Sclerosis: Theory and Practice

TDP43 aggregation at ER-exit sites impairs ER-to-Golgi transport

A framework for sharing of clinical and genetic data for precision medicine applications

Analysis of proteome-wide degradation dynamics in ALS SOD1 iPSC-derived patient neurons reveals disrupted VCP homeostasis

Globally reduced N6-methyladenosine (m6A) in C9ORF72-ALS/FTD dysregulates RNA metabolism and contributes to neurodegeneration

Butyrate endows extraocular muscle stem cell-like transcriptomic patterns that ameliorate satellite cell depletion and denervation to slow ALS progression

Deficient Sarcolemma Repair in ALS: A Novel Mechanism with Therapeutic Potential

Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis

Association of Variants in the SPTLC1 Gene With Juvenile Amyotrophic Lateral Sclerosis.

ALSUntangled #63: ketogenic diets.

Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD.

Global alterations to the choroid plexus blood-CSF barrier in amyotrophic lateral sclerosis.

Validation of serum neurofilaments as prognostic and potential pharmacodynamic biomarkers for ALS

Collaborators (30)

Ernest Fraenkel

Christopher McDermott

Rong Wu

Ashley Jones

Frank Baas

Marka van Blitterswijk

Jennifer Phillips-Cremins

Ang Li

Suvankar Pal

Bradley Smith

Andrew Brown

Russell McLaughlin

Sandra D'Alfonso

Paola Caroppo

Paolo Volanti

Michael Sendtner

Johnathan Cooper‐Knock

Viviana Pensato

Danny Miller

Jeffrey D. Rothstein

simon topp

Yingzhi Ye

Kelly Williams

Garth Nicholson

Marcella Zollino

Stuart Pickering-Brown

Shuying Sun

Caroline Vance

Oleg Butovsky

Francesca Brett

Make your next move.