M. Fatima Piedade

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Assistant Professor

Universidade de Aveiro

Portugal

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About

Dr. M. Fatima Piedade is an Assistant Professor at Universidade de Lisboa in Portugal. Her research focuses on the structural properties and stability of organic compounds, including the study of hydrogen bonding in fumaric acid, the effects of ruthenium complexes on necroptosis, and targeted therapies for breast cancer. She also investigates crystallization processes and the development of drug delivery platforms, contributing significantly to areas such as diabetes management and molecular biophysics.

Recent Grants

Grant: Close

Do desenvolvimento de novos produtos bioactivos à descoberta de novos materiais funcionais: uma abordagem estrutural em áreas emergentes

Open Date: 2013-06-01

Close Date: 2016-12-31

Grant: Close

BioMOFs - Materiais supramoleculares para aplicações biomédicas

Open Date: 2012-03-21

Close Date: 2014-09-20

Grant: Close

Complexos de Ruténio para aplicação anti-tumoral

Open Date: 2010-01-01

Close Date: 2013-06-30

Grant: Close

Síntese e estudo de compostos organometálicos/coordenação como comutadores moleculares para as tecnologias da optoelectrónica e fotónica

Open Date: 2008-12-01

Close Date: 2012-11-30

Grant: Close

Síntese de Materiais Organometálicos Moleculares e Poliméricos com Propriedades de Óptica Não Linear

Open Date: 2008-01-01

Close Date: 2011-01-01

Articles (13)

We report a drug delivery system containing a cytotoxic ruthenium complex tethered to a FGFR-targeting peptide. The system showed controlled release of the active complex in breast cancer cells resulting in improved antiproliferative activity and selectivity.

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2024

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2024

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2022

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2022

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2022

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2021

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2021

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2021

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2020

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2020

Collaborators (19)

Joaquim Ramos

Universidade de Aveiro

PORTUGAL

M. Fatima Piedade

Research Interests

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About

Recent Grants

Articles (13)

Dual FGFR-targeting and pH-activatable ruthenium–peptide conjugates for targeted therapy of breast cancer

Structure, Cohesion Energetics, and Hydrogen Bonding Cooperativity in Fumaric Acid and Alkyl Fumarates: Insights from Experiment and Theory

Necroptosis induced by ruthenium (II) complexes as mitochondrial disruptors

pH-Dependent Crystallization of 2-, 4-, 5-, and 6-Hydroxynicotinic Acids in Aqueous Media

Solubility and Crystallization Studies of Picolinic Acid

Corrigendum to: Synthesis of Substituted 4-Arylamino-1,2-naphthoquinones in One-Pot Reactions Using CotA-Laccase as Biocatalyst (Advanced Synthesis &amp; Catalysis, (2020), 362, 16, (3380-3387), 10.1002/adsc.202000082)

Improvement of Glycaemia and Endothelial Function by a New Low-Dose Curcuminoid in an Animal Model of Type 2 Diabetes

Dehydroroyleanone as a Building Block for a Drug Delivery Platform Based on Self-Assembled Nanoparticles: Structural Studies and Chemical Modification

First and Second Dissociation Enthalpies in Bi-Component Crystals Consisting of Maleic Acid and L-Phenylalanine

Structure, thermal properties and molecular mobility in cholesteryl hydrogen phthalate: Different approaches to the crystal, the glassy crystal and the mesophase

Cu(<scp>i</scp>) complexes as new antiproliferative agents against sensitive and doxorubicin resistant colorectal cancer cells: synthesis, characterization, and mechanisms of action

Half-Sandwich Cyclopentadienylruthenium(II) Complexes: A New Antimalarial Chemotype

Synthesis of Substituted 4‐Arylamino‐1,2‐naphthoquinones in One‐Pot Reactions Using CotA‐Laccase as Biocatalyst

Collaborators (19)

Joaquim Ramos

Herminio Diogo

Díaz Lanza Ana M.

Isabel Correia

Ana Catarina Sousa

Maria Paula Robalo

matteo lusi

Carlos Fontes Ribeiro

Cláudio Lousada

Tânia S. Morais

Manuel Minas da Piedade

Lígia O. Martins

Ruben Valente

Catarina V. Esteves

Sónia Silva

Célia Cabral

Lia Ascensão

Jaime A. S. Coelho

Antoni F. Roig-Navarro

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Corrigendum to: Synthesis of Substituted 4-Arylamino-1,2-naphthoquinones in One-Pot Reactions Using CotA-Laccase as Biocatalyst (Advanced Synthesis & Catalysis, (2020), 362, 16, (3380-3387), 10.1002/adsc.202000082)