Tânia S. Morais

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Universidade de Aveiro

Portugal

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Recent Grants

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Ruthenium-peptide conjugates: arrows for selectively targeting breast cancer

Open Date: 2021-03-01

Close Date: 2024-02-01

Grant: Close

Ruthenium-peptide drugs: new bullets to fight breast cancer

Open Date: 2019-05-01

Close Date:

Grant: Close

IMPACT/RISE - Innovative peptides against cancer and pathogenic bacteria

Open Date: 2015-04-01

Close Date: 2015-10-01

Grant: Close

Evaluation of the potential anti-tumoral properties of new ruthenium bioorganometallic compound

Open Date: 2009-09-01

Close Date: 2014-10-01

Articles (11)

We report a drug delivery system containing a cytotoxic ruthenium complex tethered to a FGFR-targeting peptide. The system showed controlled release of the active complex in breast cancer cells resulting in improved antiproliferative activity and selectivity.

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2024

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2023

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2021

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2021

Collaborators (16)

Filipa Mendes

Universidade de Aveiro

PORTUGAL

Tânia S. Morais

Research Interests

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Recent Grants

Articles (11)

Dual FGFR-targeting and pH-activatable ruthenium–peptide conjugates for targeted therapy of breast cancer

Copper(I)‐Thiosemicarbazone Complexes with Dual Anticancer and Antiparasitic Activity

Broad Spectrum Functional Activity of Structurally Related Monoanionic Au(III) Bis(Dithiolene) Complexes

Design and Anticancer Properties of New Water-Soluble Ruthenium–Cyclopentadienyl Complexes

Are smart delivery systems the solution to overcome the lack of selectivity of current metallodrugs in cancer therapy?

Cu(i) complexes as new antiproliferative agents against sensitive and doxorubicin resistant colorectal cancer cells: synthesis, characterization, and mechanisms of action

Ultrasonication Improves Solid Phase Synthesis of Peptides Specific for Fibroblast Growth Factor Receptor and for the Protein-Protein Interface RANK-TRAF6

Binding of RuCp complexes with human apo-transferrin: fluorescence spectroscopy and molecular docking methods

Gold(I) Bis(1,2,3-triazol-5-ylidene) Complexes as Promising Selective Anticancer Compounds

Bioconjugate Supramolecular Pd2+ Metallacages Penetrate the Blood Brain Barrier In Vitro and In Vivo

Emerging Molecular Receptors for the Specific-Target Delivery of Ruthenium and Gold Complexes into Cancer Cells

Collaborators (16)

Filipa Mendes

Marta Martins

Maria Paula Robalo

Fernanda Marques

Inês Bártolo

Miguel Prudêncio

Paulo J. Costa

Sílvia A Sousa

Maria José Villa de Brito

Filipa Pedro Costa Santos

M. Fatima Piedade

Maria Helena Garcia

Ruben Valente

Lurdes Gano

Jorge H. Leitão

Jaime A. S. Coelho

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