Manfred Kopf

Professor

ETH Zürich

Switzerland

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Professor Manfred Kopf is a faculty member at ETH Zürich, Switzerland. His research focuses on immune responses related to respiratory infections, inflammation, and the immune system's interaction with microbial ecosystems. Recent publications include studies on GM-CSF, IL-6, and the thioredoxin system, contributing valuable insights into cancer biology and viral defense mechanisms.

Articles (14)

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2025

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2025

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2025

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2023

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2022

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2022

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2022

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2022

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2022

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2022

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2022

Collaborators (14)

Annika Hausmann

Københavns Universitet

DENMARK

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Metello Innocenti

University of Milano-Bicocca

ITALY

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Chloe H. Lee

University of Oxford

UNITED KINGDOM

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Zacharias Kontarakis

Head of GEML

Eidgenössische Technische Hochschule Zürich

SWITZERLAND

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Hiu Man Grisch-Chan

University of Zurich

SWITZERLAND

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Isabelle C. Arnold

Assistant Professor

University of Zurich

SWITZERLAND

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Ari Molofsky

Associate Professor

University of California, San Francisco

UNITED STATES

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Christoph Schneider

University of Zurich

SWITZERLAND

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Gerald Schwank

Associate Professor

University of Zurich

SWITZERLAND

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Lukas Schmidheini

ETH Zurich

SWITZERLAND

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Michael Cangkrama

Senior Researcher (Oberassistent-Lecturer)

ETH Zürich

SWITZERLAND

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Basak Corak

University of Zurich

SWITZERLAND

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Hubert Rehrauer

SWITZERLAND

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Burkhard Becher

University of Zurich

SWITZERLAND

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Manfred Kopf

Research Interests

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Articles (14)

GM-CSF derived from alveolar type 2 cells promotes CD301b⁺ cDC2 generation and allergic airway inflammation

IL-6 mediates defense against influenza virus by promoting protective antibody responses but not innate inflammation

Investigating Polyreactivity of CD4+ T Cells to the Intestinal Microbiota

IL-1 protects from fatal systemic candidiasis in mice by inhibiting oxidative phosphorylation and hypoxia

The thioredoxin system: Balancing redox responses in immune cells and tumors

A Protumorigenic mDia2–MIRO1 Axis Controls Mitochondrial Positioning and Function in Cancer-Associated Fibroblasts

Monocyte-derived alveolar macrophages autonomously determine severe outcome of respiratory viral infection

LCMV induced downregulation of HVEM on antiviral T cells is critical for an efficient effector response

High-resolution profiling of MHC II peptide presentation capacity reveals SARS-CoV-2 CD4 T cell targets and mechanisms of immune escape.

Gene therapy of Csf2ra deficiency in mouse fetal monocyte precursors restores alveolar macrophage development and function

Loss of Rnf31 and Vps4b sensitizes pancreatic cancer to T cell-mediated killing.

KappaBle fluorescent reporter mice enable low-background single-cell detection of NF-κB transcriptional activity in vivo

In vivo prime editing of a metabolic liver disease in mice.

Peroxisomes Are Critical for the Development and Maintenance of B1 and Marginal Zone B Cells but Dispensable for Follicular B Cells and T Cells

Collaborators (14)

Annika Hausmann

Metello Innocenti

Chloe H. Lee

Zacharias Kontarakis

Hiu Man Grisch-Chan

Isabelle C. Arnold

Ari Molofsky

Christoph Schneider

Gerald Schwank

Lukas Schmidheini

Michael Cangkrama

Basak Corak

Hubert Rehrauer

Burkhard Becher

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