Manuel Goncalves

Associate professor

Leiden University

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Articles (12)

Collaborators (2)

Jan Wijnholds

Associate Prof

Leiden University Medical Center

Richard Frock

Assistant Professor

Stanford University School of Medicine

UNITED STATES

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Manuel Goncalves

Research Interests

Explore related searches

Contact this professor

Articles (12)

Collaborators (2)

Jan Wijnholds

Richard Frock

Make your next move.

Manuel Goncalves

Research Interests

Explore related searches

Contact this professor

Articles (12)

On RNA-programmable gene modulation as a versatile set of principles targeting muscular dystrophies

Selection-free precise gene repair using high-capacity adenovector delivery of advanced prime editing systems rescues dystrophin synthesis in DMD muscle cells

AAV-vectored base editor trans-splicing delivers dystrophin repair

Efficient and scalable generation of primordial germ cells in 2D culture using basement membrane extract overlay

Precise homology-directed installation of large genomic edits in human cells with cleaving and nicking high-specificity Cas9 variants

High-capacity adenovector delivery of forced CRISPR-Cas9 heterodimers fosters precise chromosomal deletions in human cells

Large-scale genome editing based on high-capacity adenovectors and CRISPR-Cas9 nucleases rescues full-length dystrophin synthesis in DMD muscle cells

Precise and broad scope genome editing based on high-specificity Cas9 nickases

Broadening the reach and investigating the potential of prime editors through fully viral gene-deleted adenoviral vector delivery

A primer to gene therapy: Progress, prospects, and problems

Novel Therapeutic Approaches for the Treatment of Retinal Degenerative Diseases: Focus on CRISPR/Cas-Based Gene Editing

Integrating gene delivery and gene-editing technologies by adenoviral vector transfer of optimized CRISPR-Cas9 components

Collaborators (2)

Jan Wijnholds

Richard Frock

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