Manuel Mayr

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Prof of Cardiovascular Proteomics

Imperial College London

United Kingdom

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About

Professor Manuel Mayr is a leading academic in the field of Cardiovascular Proteomics at Imperial College London, UK. His research focuses on precision medicine, cardiac regeneration, and the molecular mechanisms underlying cardiovascular diseases. Recent publications include studies on proteomic and clinical assay discordance, as well as the effects of age and metabolic stress on vascular smooth muscle cells. Professor Mayr's work integrates advanced transcriptomics and lipidomics to enhance cardiovascular risk prediction and understanding of disease mechanisms.

Recent Grants

Grant: Close

Proteomics to Explore Mechanistic Links between Circulating MiRNAs and Response to Vascular Injury

Open Date: 2013-05-01

Close Date: 2018-04-30

Grant: Close

A MicroRNA Signature for Risk of Type II Diabetes

Open Date: 2013-03-19

Close Date: 2015-03-18

Grant: Close

Endothelial MicroRNA 126 as Biomarker Candidate for Diabetic Retinopathy

Open Date: 2011-09-01

Close Date: 2014-02-28

Grant: Close

The validation of cMyBP-C as a new diagnostic marker of myocardial infarction

Open Date: 2010-11-01

Close Date: 2013-10-31

Grant: Close

Proteomic analysis of endothelial progenitor cells

Open Date:

Close Date:

Articles (20)

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2022

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2022

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2022

Collaborators (24)

Xiaoke Yin

King’s College London

UNITED KINGDOM

Manuel Mayr

Research Interests

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About

Recent Grants

Articles (20)

Precision medicine requires precision proteomics: Discordance between proteomic and clinical assays in UK Biobank

Cardiac regeneration beyond stem cells: harnessing sarcomere dynamics and endogenous repair mechanisms

ECM Modifications Driven by Age and Metabolic Stress Directly Promote Vascular Smooth Muscle Cell Osteogenic Processes

Cervical Artery Tortuosity Is Associated With Dissection Occurrence and Late Recurrence: A Nested Case-Control Study

Dissecting the effect of genetic variants on atherosclerosis: integrating bulk and single-cell transcriptomics

Longitudinal Lipidomic Signature of Coronary Heart Disease in American Indian People

Differential effects of physiological agonists on the proteome of platelet‐derived extracellular vesicles

Enhancing cardiovascular risk prediction through proteomics?

Desmosomal protein degradation as an underlying cause of arrhythmogenic cardiomyopathy.

Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein

Proteomics and lipidomics in atherosclerotic cardiovascular disease risk prediction

Reducing reductionism: addressing risk for atherosclerotic cardiovascular disease by apolipoprotein proteomics

Phenylalanine-tRNA aminoacylation is compromised by ALS/FTD-associated C9orf72 C4G2 repeat RNA

Uncovering Protein Networks in Cardiovascular Proteomics

Letter by Gutmann et al Regarding Article, “Circulating MicroRNA-122-5p Is Associated With a Lack of Improvement in Left Ventricular Function After Transcatheter Aortic Valve Replacement and Regulates Viability of Cardiomyocytes Through Extracellular Vesicles”

Human blood vessel organoids reveal a critical role for CTGF in maintaining microvascular integrity

Inhibition of miR-199a-3p in a murine hypertrophic cardiomyopathy (HCM) model attenuates fibrotic remodeling

Extracellular Matrix Profiling and Disease Modelling in Engineered Vascular Smooth Muscle Cell Tissues

Temporal in vivo platelet labeling in mice reveals age-dependent receptor expression and conservation of specific mRNAs

SGLT2 inhibitors in heart failure: insights from plasma proteomics

Collaborators (24)

Xiaoke Yin

Walter Speidl

Jeroen Demmers

Wolfgang Koenig

Erik S G Stroes

Timothy Warner

Guanhong Miao

Thomas A. Zelniker

Eva van Rooij

Alan Stitt

Oliver Fiehn

Manu Shankar-Hari

Nick S Nurmohamed

Milena Bellin

Guy A Rouleau

Adam Fellows

Anna Zampetaki

Paul Armstrong

Lingfang Zeng

Alberico Luigi Catapano

MAURO GIACCA

Michael Knoflach

Giovanni Mann

Michael Malim

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