Marcello Leopoldo

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University of Bari Aldo Moro

Italy

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Recent Grants

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Modulacja procesów zapalnych z zastosowaniem nowych agonistów receptorów formylowych ALX/FPR2 jako nowa strategia terapeutyczna depresji

Open Date: 2018-01-01

Close Date: 2020-01-01

Grant: Close

Finanziamento delle attività base di ricerca

Open Date: 2017-01-01

Close Date: 2017-01-01

Grant: Close

Searching for the new lead structures for 5-HT7 serotonin receptor ligands with increased metabolic stability

Open Date: 2016-01-01

Close Date: 2016-01-01

Grant: Close

Evaluation of serotonin type 7 (5-HT7) receptor agonists as novel drugs for the treatment of Fragile X Syndrome

Open Date: 2013-01-01

Close Date: 2017-01-01

Grant: Close

Preclinical evaluation of serotonin type 7 (5-HT7) receptor agonists as novel pharmacological tools in Fragile X Syndrome

Open Date: 2013-01-01

Close Date: 2014-01-01

Articles (14)

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2024

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2024

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2023

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2022

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2020

Collaborators (5)

Magdalena Regulska

POLAND

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Nicola A. Colabufo

ITALY

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Enza Lacivita

Associate Professor

University of Bari Aldo Moro

ITALY

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Carmen Abate

Associate Professor

University of Bari Aldo Moro

ITALY

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Agnieszka Basta-Kaim

Institute of Pharmacology

POLAND

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Marcello Leopoldo

Research Interests

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Contact this professor

Recent Grants

Articles (14)

Multitarget-Directed Ligands Hitting Serotonin Receptors: A Medicinal Chemistry Survey

Allosteric Modulators of Serotonin Receptors: A Medicinal Chemistry Survey

Structure-Activity Relationships and Therapeutic Potential of Purinergic P2X7 Receptor Antagonists

Microglia Depletion Attenuates the Pro-Resolving Activity of the Formyl Peptide Receptor 2 Agonist AMS21 Related to Inhibition of Inflammasome NLRP3 Signalling Pathway: A Study of Organotypic Hippocampal Cultures

Stimulation of Formyl Peptide Receptor-2 by the New Agonist CMC23 Protects against Endotoxin-Induced Neuroinflammatory Response: A Study in Organotypic Hippocampal Cultures

In Vitro and In Silico Analysis of the Residence Time of Serotonin 5-HT7 Receptor Ligands with Arylpiperazine Structure: A Structure–Kinetics Relationship Study

Design and Synthesis of Arylpiperazine Serotonergic/Dopaminergic Ligands with Neuroprotective Properties

LC–MS/MS Analysis on Infusion Bags and Filled Syringes of Decitabine: New Data on Physicochemical Stability of an Unstable Molecule

The Need To Improve Reporting of the Pharmacological Action of New Molecules

The N-Formyl Peptide Receptor 2 (FPR2) Agonist MR-39 Improves Ex Vivo and In Vivo Amyloid Beta (1–42)-Induced Neuroinflammation in Mouse Models of Alzheimer’s Disease

Formyl peptide receptor 2, as an important target for ligands triggering the inflammatory response regulation: a link to brain pathology

Knowledge-Based Design of Long-Chain Arylpiperazine Derivatives Targeting Multiple Serotonin Receptors as Potential Candidates for Treatment of Autism Spectrum Disorder

G-Protein Coupled Receptors Involved in the Resolution of Inflammation: Ligands and Therapeutic Perspectives

Why PB28 Could Be a Covid 2019 Game Changer?

Collaborators (5)

Magdalena Regulska

Nicola A. Colabufo

Enza Lacivita

Carmen Abate

Agnieszka Basta-Kaim

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