Marie Jose Goumans

Professor

Leiden University Medical Center

Netherlands

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Professor Marie Jose Goumans is a faculty member at the Leiden University Medical Center in the Netherlands. Her research focuses on myocardial infarction treatment strategies, cardiac fibrosis, and the role of TGF-β signaling in various cardiovascular conditions. She has made significant contributions to the understanding of angiogenesis and the immune response in heart valve biology, as well as the effects of cyclic strain on cardiac fibroblast behavior.

Articles (20)

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2025

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2022

Collaborators (10)

Anke Smits

Assistant Professor

Leiden University Medical Center

NETHERLANDS

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Li Qian

University of North Carolina

UNITED STATES

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Jaap den Toonder

Prof. Dr. Ir. at Eindhoven University of Technology

Eindhoven University of Technology

NETHERLANDS

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Joost Sluijter

Professor of Cellar and translational Cardiology

University Medical Center Groningen

NETHERLANDS

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Ye Wang

Eindhoven University of Technology

NETHERLANDS

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Daniël A Pijnappels

Leiden University Medical Center

NETHERLANDS

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Robert Passier

Professor

Leiden University Medical Center

NETHERLANDS

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Paul H. A. Quax

Leiden University Medical Center

NETHERLANDS

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Carlijn Bouten

Professor at Eindhoven University of Technology

Eindhoven University of Technology

NETHERLANDS

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Bart Loeys

BELGIUM

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Marie Jose Goumans

Research Interests

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About

Articles (20)

Preclinical extracellular matrix-based treatment strategies for myocardial infarction: a systematic review and meta-analysis

Immune Shielding of Human Heart Valves

A New Ex Vivo Model to Study Cardiac Fibrosis in Whole Mouse Hearts

Targeting Soluble TGF-β Factors

Angiogenesis in Chronic Thromboembolic Pulmonary Hypertension: A Janus-Faced Player?

Vitamin C facilitates direct cardiac reprogramming by inhibiting reactive oxygen species

TGF-β receptor-specific NanoBRET Target Engagement in living cells for high-throughput kinase inhibitor screens

Cyclic strain has antifibrotic effects on the human cardiac fibroblast transcriptome in a human cardiac fibrosis-on-a-chip platform

Methacrylated human recombinant collagen peptide as a hydrogel for manipulating and monitoring stiffness-related cardiac cell behavior

Sex-biased TGFβ signalling in pulmonary arterial hypertension

Long-Term Effects of Pulmonary Endarterectomy on Right Ventricular Stiffness and Fibrosis in Chronic Thromboembolic Pulmonary Hypertension

Molecular mechanisms and targets of right ventricular fibrosis in pulmonary hypertension

Human pluripotent stem cell-derived cardiomyocytes align under cyclic strain when guided by cardiac fibroblasts

Chasing youth on the outside: unique features of the human fetal epicardium

SMAD6-deficiency in human genetic disorders

Go with the flow…..

R-SMAD in control of the R-smooth muscle cell

Conditional immortalization of human atrial myocytes for the generation of in vitro models of atrial fibrillation

Inhibition of the prolyl isomerase Pin1 improves endothelial function and attenuates vascular remodelling in pulmonary hypertension by inhibiting TGF-beta signalling

Interfering in the ALK1 Pathway Results in Macrophage-Driven Outward Remodeling of Murine Vein Grafts

Collaborators (10)

Anke Smits

Li Qian

Jaap den Toonder

Joost Sluijter

Ye Wang

Daniël A Pijnappels

Robert Passier

Paul H. A. Quax

Carlijn Bouten

Bart Loeys

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