Mario Mauthe

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Assisten Professor

University Medical Center Groningen

Netherlands

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About

Mario Mauthe is an Assistant Professor at the University Medical Center Groningen in the Netherlands. His research focuses on autophagy, mitochondrial dysfunction, and their implications for neurodegenerative diseases, as evidenced by his recent publications. Notable articles include investigations into aggrephagy mechanisms, the role of autophagy in mitochondrial membrane protein-associated neurodegeneration, and the impact of inflammatory processes on autophagy-related genes in multiple sclerosis.

Recent Grants

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Identifying and characterizing the multiple cellular roles of WDR45 in BPAN

Open Date: 2018-09-01

Close Date: 2019-08-01

Articles (10)

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2025

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2025

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2023

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2023

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2023

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2023

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2022

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2022

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2021

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2021

Collaborators (15)

jingyue jia

Assistant Professor

University of New Mexico

UNITED STATES

Mario Mauthe

Research Interests

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About

Recent Grants

Articles (10)

Aggregate fragmentation: the ticket to aggrephagy

A chaperone-proteasome-based fragmentation machinery is essential for aggrephagy

Mitochondrial dysfunction mediates neuronal cell response to DMMB photodynamic therapy.

Identification of Autophagy as a Functional Target Suitable for the Pharmacological Treatment of Mitochondrial Membrane Protein-Associated Neurodegeneration (MPAN) In Vitro

A burning question from the first international BPAN symposium: is restoration of autophagy a promising therapeutic strategy for BPAN?

Mitochondrial protein BNIP3 regulates Chikungunya virus replication in the early stages of infection

Digest it all: the lysosomal turnover of cytoplasmic aggregates.

Transcriptomic changes in autophagy-related genes are inversely correlated with inflammation and are associated with multiple sclerosis lesion pathology

ATG9A protects the plasma membrane from programmed and incidental permeabilization.

WDR45, one gene associated with multiple neurodevelopmental disorders

Collaborators (15)

jingyue jia

Vojo Deretic

Arie Geerlof

Harm Kampinga

Meriem GARFA TRAORE

Marina AJ Tijssen

Dineke Verbeek

Bart J. L. Eggen

Sabine Schipper-Krom

Marina Trombetta Lima

Fulvio Reggiori

Amalia Dolga

Mark Hipp

Ruheena Javed

Ana Messias

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