Bart J. L. Eggen

University Name

Netherlands

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Research Interests

Immunology

70%

Neurology

100%

Glia

100%

Inflammatory Biology

90%

Neuroinflammation

80%

Myelination

60%

Microglia

50%

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Articles29

Beyond the nuclear border: single-cell analysis of in situ sequenced human brain tissue using cellular features

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Year:

2025

WDR49‐Positive Astrocytes Mark Severity of Neurodegeneration in Frontotemporal Lobar Degeneration and Alzheimer's Disease

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Year:

2025

Schizophrenia-associated changes in neuronal subpopulations in the human midbrain

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Year:

2025

Calorie restriction increases the sensitivity of progeroid Ercc1Δ/− mice to acute (neuro)inflammation

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Year:

2025

Microglia regulate myelin clearance and cholesterol metabolism after demyelination via interferon regulatory factor 5

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Year:

2025

Unboxing “Omics” in Glial Biology to Understand Neurological Disease

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Year:

2025

Early amyloid‐induced changes in microglia gene expression in male <scp>APP</scp>/<scp>PS1</scp> mice

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Year:

2024

ATP5PO levels regulate enteric nervous system development in zebrafish, linking Hirschsprung disease to Down Syndrome

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Year:

2024

Cellular senescence in brain aging and neurodegeneration

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Year:

2024

The role of microglia in early neurodevelopment and the effects of maternal immune activation

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Year:

2024

Identification of clinical disease trajectories in neurodegenerative disorders with natural language processing

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Year:

2024

Glioblastoma and its treatment are associated with extensive accelerated brain aging

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Year:

2024

Single-Nucleus RNA-Seq Characterizes the Cell Types Along the Neuronal Lineage in the Adult Human Subependymal Zone and Reveals Reduced Oligodendrocyte Progenitor Abundance with Age

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Year:

2024

Sex-dependent APOE4 neutrophil–microglia interactions drive cognitive impairment in Alzheimer’s disease

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Year:

2024

Brain organoid models for studying the function of iPSC-derived microglia in neurodegeneration and brain tumours

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Year:

2024

Spatially resolved gene signatures of white matter lesion progression in multiple sclerosis

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Year:

2024

Cold Mechanical Isolation of Placental Macrophages as a Method to Limit Procedure-Induced Activation of Macrophages

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Year:

2023

Microglia morphotyping in the adult mouse CNS using hierarchical clustering on principal components reveals regional heterogeneity but no sexual dimorphism

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Year:

2023

How the cGAS–STING system links inflammation and cognitive decline

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Year:

2023

Pathological ultrastructural alterations of myelinated axons in normal appearing white matter in progressive multiple sclerosis

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Year:

2023

APOE4 impairs the microglial response in Alzheimer’s disease by inducing TGFβ-mediated checkpoints

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Year:

2023

Microglia Transcriptional Profiling in Major Depressive Disorder Shows Inhibition of Cortical Gray Matter Microglia

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Year:

2023

Single-nucleus RNA sequencing of midbrain blood-brain barrier cells in schizophrenia reveals subtle transcriptional changes with overall preservation of cellular proportions and phenotypes

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Year:

2022

Transcriptomic changes in autophagy-related genes are inversely correlated with inflammation and are associated with multiple sclerosis lesion pathology

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Year:

2022

Exploring reported genes of microglia RNA-sequencing data

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Year:

2021

Regionally diverse astrocyte subtypes and their heterogeneous response to EAE

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Year:

2021

The effects of postmortem delay on mouse and human microglia gene expression

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Year:

2021

Type I interferon‐activated microglia are critical for neuromyelitis optica pathology

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Year:

2021

Human fetal microglia acquire homeostatic immune-sensing properties early in development

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Year:

2020

Collaborators18

Agnieszka Wlodarczyk

University of Southern Denmark

DENMARK

Ben N. G. Giepmans

NETHERLANDS

Jelmer R. Prins

University of Groningen

NETHERLANDS

Mario Mauthe

Assisten Professor

University Medical Center Groningen

NETHERLANDS

Annemieke J.M. Rozemuller

Professor Neuropathology

NETHERLANDS

Tsuneya Ikezu

Professor

Mayo Clinic

UNITED STATES

Karel Scheepstra

Amsterdam UMC Locatie VUmc

NETHERLANDS

Amanda Sierra

Research Professor and Group Leader

SPAIN

Jonathan Weinstein

UNITED STATES

Emma Gerrits

Karolinska Institutet

SWEDEN

Mark Verheijen

NETHERLANDS

Marina Trombetta Lima

Assistant Professor

University of Groningen

NETHERLANDS

Steven Bergink

assistant professor/senior lecturer

NETHERLANDS

Erwin Brosens

Erasmus University Rotterdam

NETHERLANDS

Cynthia Shannon Weickert

Professor

SUNY Upstate Medical University

UNITED STATES

Jean Paul Chadarevian

University of California, Irvine

UNITED STATES

Trevor Owens

University of Southern Denmark

DENMARK

Johan A. Slotman

Erasmus University Rotterdam

NETHERLANDS

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