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Marja Koskuvi

University of Helsinki

Finland

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Research Interests

Computational Neuroscience

30%

Systems Neuroscience

40%

Glia

70%

Neuroscience

50%

Neuroprotection

50%

Schizophrenia

40%

Neurodegenerative Disease

40%

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Articles17

miRNA profiling of hiPSC-derived neurons from monozygotic twins discordant for schizophrenia

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Year:

2025

Inflammation-induced lysosomal dysfunction in human iPSC-derived microglia is exacerbated by APOE 4/4 genotype.

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Year:

2025

Kynurenic Acid and Promotion of Activity-Dependent Synapse Elimination in Schizophrenia.

Article Link

Year:

2025

Frontotemporal dementia patient-derived iPSC neurons show cell pathological hallmarks and evidence for synaptic dysfunction and DNA damage

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Year:

2025

Lower complement C1q levels in first-episode psychosis and in schizophrenia.

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Year:

2024

Astrocytes Regulate Neuronal Network Burst Frequency Through NMDA Receptors in a Species- and Donor-Specific Manner

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Year:

2024

Genetic contribution to microglial activation in schizophrenia

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Year:

2024

Integrative metabolomics-genomics analysis identifies key networks in a stem cell-based model of schizophrenia

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Year:

2024

Human PSEN1 Mutant Glia Improve Spatial Learning and Memory in Aged Mice

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Year:

2022

Contribution of astrocytes to familial risk and clinical manifestation of schizophrenia

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Year:

2022

Astrocyte Progenitors Derived From Patients With Alzheimer Disease Do Not Impair Stroke Recovery in Mice

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Year:

2022

The iPSC perspective on schizophrenia

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Year:

2022

Microglia-like Cells Promote Neuronal Functions in Cerebral Organoids

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Year:

2021

Molecular signaling pathways underlying schizophrenia

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Year:

2021

Generation of a human induced pluripotent stem cell line (UEFi003-A) carrying heterozygous A673T variant in amyloid precursor protein associated with a reduced risk of Alzheimer's disease

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Year:

2020

Metabolic alterations in Parkinson's disease astrocytes.

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Year:

2020

NF-E2-related factor 2 activation boosts antioxidant defenses and ameliorates inflammatory and amyloid properties in human Presenilin-1 mutated Alzheimer's disease astrocytes

Article Link

Year:

2020

Collaborators14

Pinja Kettunen

University of Helsinki

FINLAND

Katharina Günther

University of Innsbruck

AUSTRIA

Helena Fatouros-Bergman

Karolinska Institutet

SWEDEN

Lesley Cheng

La Trobe University

AUSTRALIA

Anastasia Ludwig

University of Helsinki

FINLAND

Iiris Hovatta

University of Helsinki

FINLAND

Jari Koistinaho

University of Helsinki

FINLAND

Sophie Erhardt

Chair, Department of Physiology and Pharmacology

Karolinska Institutet

SWEDEN

Meike Hedwig Keuters

University of Helsinki

FINLAND

Tristen Hewitt

University of Helsinki

FINLAND

Jari Tiihonen

Karolinska Institutet

SWEDEN

Olli Pietilainen

University of Helsinki

FINLAND

Alfredo Ramirez

University of Texas Health Science Center at San Antonio

UNITED STATES

Anni-Maija Linden

University of Helsinki

FINLAND

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