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Mark Dillingham

University of Bristol

United Kingdom

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Research Interests

Cell Biology

50%

Biochemistry

70%

Molecular Biology

50%

Protein Synthesis

20%

Dna Replication

20%

Genome Engineering

20%

Gene Transfer

20%

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Recent Grants

Grant: Close

Single-molecule analysis of double-stranded DNA break repair in living bacteria

Open Date: 2019-03-01

Close Date: 2022-02-28

Grant: Close

DNA-Repairman: Regulated Assembly of Molecular Machines for DNA repair: a Molecular Analysis Training Network.

Open Date: 2017-01-01

Close Date: 2021-01-01

Grant: Close

New baculovirus-based CRISPR/Cas tools for genome engineering.

Open Date: 2017-01-01

Close Date: 2020-01-01

Grant: Close

South West Regional Facility for High-Resolution Electron Cryo-Microscopy

Open Date: 2016-11-01

Close Date: 2021-11-01

Grant: Close

Provision of high-resolution proteomics to enhance forward and back translational research.

Open Date: 2014-09-01

Close Date: 2019-08-31

Articles10

Targeted control of pneumolysin production by a mobile genetic element in Streptococcus pneumoniae

Article Link

Year:

2022

Structures of RecBCD in complex with phage-encoded inhibitor proteins reveal distinctive strategies for evasion of a bacterial immunity hub

Article Link

Year:

2022

Highly efficient CRISPR-mediated large DNA docking and multiplexed prime editing using a single baculovirus

Article Link

Year:

2022

Towards a molecular mechanism underlying mitochondrial protein import through the TOM and TIM23 complexes

Article Link

Year:

2022

Long DNA constructs to study helicases and nucleic acid translocases using optical tweezers

Article Link

Year:

2022

Human HELB is a processive motor protein that catalyzes RPA clearance from single-stranded DNA

Article Link

Year:

2022

Analysis of the PcrA-RNA polymerase complex reveals a helicase interaction motif and a role for PcrA/UvrD helicase in the suppression of R-loops

Article Link

Year:

2021

CTP promotes efficient ParB-dependent DNA condensation by facilitating one-dimensional diffusion from parS

Article Link

Year:

2021

A stapled peptide mimetic of the CtIP tetramerization motif interferes with double-strand break repair and replication fork protection

Article Link

Year:

2021

Refined measurement of SecA-driven protein secretion reveals that translocation is indirectly coupled to ATP turnover

Article Link

Year:

2020

Collaborators15

Fernando Moreno-Herrero

Professor (Investigador Científico CSIC)

SPAIN

Angela Nobbs

University of Bristol

UNITED KINGDOM

Sarah Earle

University of Oxford

UNITED KINGDOM

Francesco Aulicino

University of Bristol

UNITED KINGDOM

Gavin Iain Welsh

University of Bristol

UNITED KINGDOM

TARCISIO BRIGNOLI

Università degli Studi di Torino

ITALY

Emily Stevens

Lecturer in Microbiology and Immunology

Kiel University

UNITED KINGDOM

Erwin Ilegems

Karolinska Institutet

SWEDEN

Seána Duggan

University of Bristol

UNITED KINGDOM

Christine Toelzer

University of Bristol

UNITED KINGDOM

Daniel Morse

Lecturer

UNITED KINGDOM

Ian Collinson

Professor of Biochemistry (following lecturer, senior lecturer and reader)

University of Bristol

UNITED KINGDOM

Alessandro Sartori

University of Zurich

SWITZERLAND

Christiane Helene Berger-Schaffitzel

Professor of Biochemistry

University of Bristol

UNITED KINGDOM

Rachel McLoughlin

Professor in Immunology

Trinity College Dublin

IRELAND

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