Micah Gearhart

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Research Assistant Professor

University of Minnesota

United States

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About

Micah Gearhart is a Research Assistant Professor at the University of Minnesota, USA. His research focuses on the molecular mechanisms of development and regeneration, with recent studies investigating protein interactions in oocyte activation, stem cell identity regulation, and genetic mutations associated with retinal degeneration. Dr. Gearhart's work encompasses areas such as genomics, cellular differentiation, and the role of specific proteins in muscular and reproductive developmental processes.

Recent Grants

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Epigenetic Control of Human Trophoblast Stem Cell Differentiation

Open Date: 2020-08-03

Close Date: 2022-06-30

Articles (14)

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2020

Collaborators (17)

David Zarkower

University of Minnesota

UNITED STATES

Micah Gearhart

Research Interests

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About

Recent Grants

Articles (14)

A sperm–oocyte protein partnership required for egg activation in Caenorhabditis elegans

Dux Is Dispensable for Skeletal Muscle Regeneration: A Study Inspired by a “Red Flagged” Publication and Editorial Oversight

Sall4 regulates posterior trunk mesoderm development by promoting mesodermal gene expression and repressing neural genes in the mesoderm

Human trophoblast stem cells restrict human cytomegalovirus replication

Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein

Genomics of sexual cell fate transdifferentiation in the mouse gonad

Mutations in BCOR , a co-repressor of CRX/OTX2 , are associated with early-onset retinal degeneration

BCOR and BCORL1 Mutations Drive Epigenetic Reprogramming and Oncogenic Signaling by Unlinking PRC1.1 from Target Genes

Lrh1 can help reprogram sexual cell fate and is required for Sertoli cell development and spermatogenesis in the mouse testis

Regulation of stem cell identity by miR-200a during spinal cord regeneration

Inactivation of the CIC-DUX4 oncogene through P300/CBP inhibition, a therapeutic approach for CIC-DUX4 sarcoma

The conserved sex regulator DMRT1 recruits SOX9 in sexual cell fate reprogramming

Insights into the Involvement of Spliceosomal Mutations in Myelodysplastic Disorders from Analysis of SACY-1/DDX41 in Caenorhabditis elegans

OFCD syndrome and extraembryonic defects are revealed by conditional mutation of the Polycomb-group repressive complex 1.1 (PRC1.1) gene BCOR

Collaborators (17)

David Zarkower

Myriam Hemberger

Tatsuya Tsukamoto

Katherine Walstrom

Pierre Mattar

Isabelle Miletich

Aimee Jaramillo-Lambert

Katherine Chen

Craig Bierle

Hideki Aihara

Darko Bosnakovski

Chenwei Wang

Yasushi Nakagawa

Michael Kyba

Yasuhiko Kawakami

Naomi Courtemanche

David Greenstein

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