Michael Kyba

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University of Minnesota

United States

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Lillehei Heart Institute AHA Summer Scholars Program

Open Date: 2021-01-01

Close Date: 2023-12-31

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Collaborators (20)

Karin E Peterson

Chief, Neuroimmunology Unit

National Institutes of Health

UNITED STATES

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Eric Batchelor

UNITED STATES

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Edgar A. Arriaga

University of Minnesota

UNITED STATES

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Manda Keller-Ross

University of Minnesota

UNITED STATES

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Rachel Rau

Associate Professor

Seattle Children's Hospital

UNITED STATES

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Hideki Aihara

Assistant/Associate Professor

University of Minnesota

UNITED STATES

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Ashok Kumar

Professor and Chair

University of Houston

UNITED STATES

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Darko Bosnakovski

University of Minnesota

UNITED STATES

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Juan Abrahante

University of Minnesota

UNITED STATES

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Sang-Ging Ong

UNITED STATES

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Jeffrey Steimle

Baylor College of Medicine

UNITED STATES

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Sinjini Gupta

Baylor College of Medicine

UNITED STATES

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Paula Stein

National Institute of Environmental Health Sciences

UNITED STATES

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Jop van Berlo

Assistant Professor

University of Minnesota

UNITED STATES

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Phablo Abreu

University of Minnesota

UNITED STATES

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Micah Gearhart

Research Assistant Professor

University of Minnesota

UNITED STATES

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Zilai Wang

Research Assistant Professor

University of Chicago

UNITED STATES

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Shaolei Xiong

University of Illinois Chicago (UIC)

UNITED STATES

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Man Liu

Assistant Professor

University of Minnesota

UNITED STATES

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Samuel Dudley

University of Minnesota

UNITED STATES

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Michael Kyba

Research Interests

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Recent Grants

Articles (25)

Matrix metalloproteinases are hallmark early biomarkers and therapeutic targets in FSHD

Long-Term Engraftment and Satellite Cell Expansion from Human PSC Teratoma-Derived Myogenic Progenitors

Dux Is Dispensable for Skeletal Muscle Regeneration: A Study Inspired by a “Red Flagged” Publication and Editorial Oversight

Estradiol deficiency as a consequence of aging contributes to the depletion of the satellite cell pool in female mice

Development of p300-targeting degraders with enhanced selectivity and onset of degradation

When everything is a master regulator, nothing is

Multiparametric identification of putative senescent cells in skeletal muscle via mass cytometry

Inducing positive inotropy in human iPSC-derived cardiac muscle by gene editing-based activation of the cardiac α-myosin heavy chain

Cardiac Development Long Non-Coding RNA (<i>CARDEL</i>) Is Activated during Human Heart Development and Contributes to Cardiac Specification and Homeostasis

The homeobox transcription factor DUXBL controls exit from totipotency

Skin muscle is the initial site of viral replication for arboviral bunyavirus infection

Pharmacological targeting of P300/CBP reveals EWS::FLI1-mediated senescence evasion in Ewing sarcoma

Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein

Facioscapulohumeral muscular dystrophy’s game of homeodomains: therapy wants a biomarker as a sword wants a whetstone

Proliferation and Maturation: Janus and the Art of Cardiac Tissue Engineering

The fibrotic niche impairs satellite cell function and muscle regeneration in mouse models of Marfan syndrome

Genetically prolonged beige fat in male mice confers long-lasting metabolic health.

DNMT3A-coordinated splicing governs the stem state switch towards differentiation in embryonic and haematopoietic stem cells

Hedgehog signaling activates a mammalian heterochronic gene regulatory network controlling differentiation timing across lineages.

Dual inhibition of MAPK and PI3K/AKT pathways enhances maturation of human iPSC-derived cardiomyocytes.

Not young but still immature: a HIF-1α–mediated maturation checkpoint in regenerating muscle

Transplantation of PSC-derived myogenic progenitors counteracts disease phenotypes in FSHD mice

The chemokine receptor CXCR4 regulates satellite cell activation, early expansion, and self-renewal, in response to skeletal muscle injury

Exercise Intolerance in Facioscapulohumeral Muscular Dystrophy

Estradiol deficiency reduces the satellite cell pool by impairing cell cycle progression

Collaborators (20)

Karin E Peterson

Eric Batchelor

Edgar A. Arriaga

Manda Keller-Ross

Rachel Rau

Hideki Aihara

Ashok Kumar

Darko Bosnakovski

Juan Abrahante

Sang-Ging Ong

Jeffrey Steimle

Sinjini Gupta

Paula Stein

Jop van Berlo

Phablo Abreu

Micah Gearhart

Zilai Wang

Shaolei Xiong

Man Liu

Samuel Dudley

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